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Urothelial Cancer: What Is the Role of Expression-based Subtypes to Guide Neoadjuvant Therapy in Muscle-invasive Bladder Cancer?
Tumor subtypes originate from the heterogeneity of bladder cancer. The goal of subtyping is to reproducibly group tumors to generate a specific outcome (eg, response to therapy). It is crucial to detect subtypes that respond better to perio…
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The changing landscape of urothelial carcinoma: on the edge of a paradigm shift.
Urothelial cancers of the urinary tract are the fourth most common malignancy in men, with a shifting demographic affecting younger patients and an increasing incidence in females. In this Review, we discuss recent discoveries and paradigm-…