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Chronic migraine and Botulinum Toxin Type A: Where do paths cross?
Migraine is a highly prevalent and disabling disorder accounted among the primary headaches. It is the expression of a complex, and not yet fully understood, pathophysiology involving the sensitization of peripheral and central nociceptive …
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Botulinum toxin for chronic migraine: Clinical trials and technical aspects.
OnabotulinumtoxinA has been approved for the prophylaxis of chronic migraine following the demonstration of efficacy in two large controlled trials. Data collected from pragmatic studies in the real-life setting have contributed important a…