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11건-
Recent Advances in Rabbit Oncology: Diseases, Diagnosis.
This review summarizes neoplastic diseases in pet rabbits, covering tumor types, clinical signs, and diagnostics. Common neoplasms include reproductive (mammary, uterine), hematopoietic, skin, and internal organ tumors, with diagnosis relyi…
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Dorocubicel: First Approval.
Dorocubicel (Zemcelpro) is a cell therapy that includes UM171-expanded CD34 haematopoietic stem cells derived from umbilical cord blood. It is being developed by Cordex Biologics for the treatment of haematological malignancies and non-mali…
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Zongertinib: First Approval.
Zongertinib (HERNEXEOS) is a small molecule, irreversible, HER2-specific tyrosine kinase inhibitor being developed by Boehringer Ingelheim for the treatment of advanced solid tumours with HER2 aberrations. Zongertinib selectively inhibits H…
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CT-guided online adaptive stereotactic body radiotherapy for pancreas ductal adenocarcinoma: Dosimetric and initial clinical experience.
[PURPOSE/OBJECTIVES] Retrospective analysis suggests that dose escalation to a biologically effective dose of more than 70 Gy may improve overall survival in patients with pancreatic ductal adenocarcinoma (PDAC), but such treatments in prac…
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Research priority setting in plastic and reconstructive surgery: A systematic review.
[BACKGROUND] The health research agenda has historically been led by researchers; however, their priorities may not necessarily align with those of patients, caregivers and clinicians. Research priority setting initiatives identify and prio…
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Open tibia/fibula in the elderly: A retrospective cohort study.
The incidence of open tibia/fibula fractures in the elderly is increasing, but current national guidelines focus on the aggressive treatment of high-energy injuries in younger patients. There is conflicting evidence regarding whether older …
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Nonlinear Changes in Botulinum Toxin Treatment of Task-Specific Dystonia during Long-Term Treatment.
Botulinum toxin (BoTX) is the standard treatment for task-specific dystonias (TSDs) such as musician's dystonia (MD). Our aim was to assess the long-term changes in BoTX treatment in a highly homogeneous and, to our knowledge, largest group…
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Approach to Tremor Disorders.
Tremor disorders are diverse and complex. Historical clues and examination features play a major role in diagnosing these disorders, but diagnosis can be challenging due to phenotypic overlap. Ancillary testing, such as neuroimaging or labo…
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Outcomes and outcome measures reported in clinical studies of therapeutic mammaplasty: a systematic review protocol.
[INTRODUCTION] Therapeutic mammaplasty (TM) is an oncological procedure which combines tumour resection with breast reduction and mastopexy techniques. Previous systematic reviews have demonstrated oncological safety of TM, but poor and inc…
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Outcome reporting in therapeutic mammaplasty: a systematic review.
[BACKGROUND] Therapeutic mammaplasty (TM) is an oncological procedure which combines tumour resection with breast reduction and mastopexy techniques. Previous systematic reviews have demonstrated the oncological safety of TM but reporting o…
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Comparison of perceptions and treatment practices between neurosurgeons and plastic surgeons for infants with deformational plagiocephaly.
[OBJECT] Deformational plagiocephaly (DP) is the leading cause of head shape abnormalities in infants. Treatment options include conservative measures and cranial molding. Pediatric neurosurgeons and craniofacial plastic surgeons have yet t…