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22건 · 최신순-
Anatomical-Functional-Aesthetic Classification of Cervical Aging: Development of the S-F-M Score and Visual Mandala Model.
[BACKGROUND] Cervical aging is a multifactorial process affecting skin quality, fat distribution, and platysmal activity, yet existing assessment tools typically address these elements in isolation. A need remains for a comprehensive, intui…
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Patient-Reported Outcomes After Treatment With OnabotulinumtoxinA for Platysma Prominence: Results From a Phase 2 Dose-Ranging Study.
[BACKGROUND] Repetitive contractions of the platysma muscle may result in vertical neck bands that blunt the jawline (i.e., platysma prominence [PP]). We report patient-reported outcomes (PROs) from a phase 2 study evaluating onabotulinumto…
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Integrating VYC-12L With Energy-Based Devices for Skin-Quality Improvement: Global Expert Considerations for Safe and Effective Outcomes.
[BACKGROUND] Energy-based devices (EBDs) and injectable hyaluronic acid gels, such as VYC-12L, are each effective treatment modalities for improving skin quality. [OBJECTIVES] To assess the rationale and potential benefits of adding VYC-12…
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Reduction of masseter muscle prominence after treatment with onabotulinumtoxinA: Primary results from a randomized phase 2 study.
[BACKGROUND] OnabotA is used to treat masseter muscle prominence (MMP). [OBJECTIVE] To assess the safety and efficacy of OnabotA for MMP in a randomized study. [METHODS] This 12-month, multicenter, double-blind, placebo-controlled, phase …
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Efficacy and Safety of RelabotulinumtoxinA Liquid Botulinum Toxin in the Treatment of Lateral Canthal Lines: Results From the Phase 3 READY-2 Study.
[BACKGROUND] RelabotulinumtoxinA (RelaBoNT-A) is a complex-free, ready-to-use, liquid botulinum toxin A. [OBJECTIVE] Efficacy/safety of RelaBoNT-A treatment for lateral canthal lines (LCL). [METHODS] Randomized adults received RelaBoNT-A …
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A Unified Approach to Facial Contours and Volume Correction: The Role of the Cheek and the Chin.
[BACKGROUND] Facial proportions and contours influence perceptions of beauty and youthfulness. In particular, the shape and definition of the midface and lower face impact the overall appearance of the face. [METHODS] This review provides …
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Effectiveness of hyaluronic acid fillers for cheek augmentation using a treatment guide to choose between products.
[BACKGROUND] Patients can have different reasons for seeking cheek augmentation; while some are in need of volume augmentation, others may request projection and lifting. A treatment guide can be useful for treating clinicians in choosing t…
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Effectiveness and Safety of a New Hyaluronic Acid Injectable for Augmentation and Correction of Chin Retrusion.
[BACKGROUND] A hyaluronic acid (HA) filler intended for non-surgical improvement of chin appearance should ideally be of high strength/firmness (high G') to allow for deep injections on the bone. HASHA (Restylane Shaype) is a new hyaluronic…
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Clinical Immunogenicity of DaxibotulinumtoxinA for Injection in Glabellar Lines: Pooled Data from the SAKURA Phase 3 Trials.
DaxibotulinumtoxinA for Injection (DAXI) is a novel botulinum toxin type A product containing daxibotulinumtoxinA with a stabilizing excipient peptide (RTP004). DAXI immunogenicity was assessed in three phase 3 glabellar line studies (two p…
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Immunogenicity of DaxibotulinumtoxinA for Injection in Glabellar Lines.
DaxibotulinumtoxinA-lanm for injection (DAXI), a novel botulinum toxin type A formulation, contains a purified 150-kD core neurotoxin (daxibotulinumtoxinA) and proprietary stabilizing peptide (RTP004), and is approved for glabellar line tre…
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Enhanced patient retention after combination vs single modality treatment using hyaluronic acid filler and neuromodulator: A multicenter, retrospective review by The Flame Group.
[BACKGROUND] It is believed that combination treatment with both neuromodulators (NM) and hyaluronic acid soft-tissue fillers (HA) results in superior aesthetic results and increased patient satisfaction compared to either treatment alone. …
- Hyaluronidase in Practice: A Survey of Dermatologic and Plastic Surgeons in the United States and Canada.
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Retrospective review of delayed adverse events secondary to treatment with a smooth, cohesive 20-mg/mL hyaluronic acid filler in 4500 patients.
[BACKGROUND] Recent publications have suggested an increased risk of delayed adverse events (DAEs) with a smooth, cohesive 20-mg/mL hyaluronic acid filler, Juvéderm Voluma (HA-V). [OBJECTIVE] To examine the occurrence of HA-V DAEs and iden…
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Update on Avoiding and Treating Blindness From Fillers: A Recent Review of the World Literature.
[BACKGROUND] Sudden loss of vision secondary to filler treatments is a rare but catastrophic complication. [OBJECTIVES] The aim of this study was to update the published cases of blindness after filler injection that have occurred since we…
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Injectable DaxibotulinumtoxinA for the Treatment of Glabellar Lines: A Phase 2, Randomized, Dose-Ranging, Double-Blind, Multicenter Comparison With OnabotulinumtoxinA and Placebo.
[BACKGROUND] Injectable daxibotulinumtoxinA (RT002) is an investigational botulinum toxin Type A in clinical development. It is formulated with a proprietary peptide and offers the potential of a longer acting neurotoxin therapy. [OBJECTIV…
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Preventive, Cumulative Effects of Botulinum Toxin Type A in Facial Aesthetics.
[BACKGROUND] Botulinum toxin Type A (BoNTA) is the gold standard for the treatment of dynamic rhytides in the face. Recently, clinical observation suggests that individuals who receive regular injections of BoNTA experience ongoing wrinkle …
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Comparing Injectable DaxibotulinumtoxinA and OnabotulinumtoxinA in Moderate and Severe Glabellar Lines: Additional Analyses From a Phase 2, Randomized, Dose-Ranging, Double-Blind, Multicenter Study.
[BACKGROUND] Injectable daxibotulinumtoxinA (RT002) is an investigational botulinum toxin Type A. Published Phase 2 data show that, compared with 20U onabotulinumtoxinA, 40U daxibotulinumtoxinA is associated with a significantly greater res…
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Sodium Deoxycholate for Submental Contouring.
The chin and jaw line are integral parts of an individual's aesthetic profile, and the presence of submental fat detracts from this and can lead to displeasure with one's facial appearance. While liposuction and cosmetic surgery are regarde…
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Overview of ATX-101 (Deoxycholic Acid Injection): A Nonsurgical Approach for Reduction of Submental Fat.
In 2015, ATX-101 (deoxycholic acid injection; Kybella in the United States and Belkyra in Canada; Kythera Biopharmaceuticals, Inc., Westlake Village, CA [an affiliate of Allergan plc, Dublin, Ireland]) was approved as a first-in-class injec…
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Delayed-onset nodules secondary to a smooth cohesive 20 mg/mL hyaluronic acid filler: cause and management.
[BACKGROUND] The shift from 2- to 3-dimensional soft tissue augmentation has allowed the development of hyaluronic acid (HA) fillers, which are long lasting and also reversible. Delayed-onset inflammatory nodules have recently been reported…
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Clinical Experience With 11,460 mL of a 20-mg/mL, Smooth, Highly Cohesive, Viscous Hyaluronic Acid Filler.
[BACKGROUND] A 3-dimensional approach to facial rejuvenation restores volume lost over time. Hyaluronic acid (HA) filling agents provide long-lasting correction with minimal side effects and a high level of patient satisfaction. The newest …
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A Pilot Study on the Treatment of Posterior Cheek Enlargement in HIV+ Patients With Botulinum Toxin A.
[BACKGROUND] Posterior cheek enlargement in human immunodeficiency virus (HIV)+ individuals can lead to significant cosmetic disfigurement. Both parotid gland and masseter muscle overlie the mandibular ramus, contributing to lower facial co…