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Efficacy and Safety of New Hyaluronic Acid Filler for Nasolabial Fold Correction: A Double-Blind, Randomized Trial.
[BACKGROUND] Nasolabial folds (NLFs) are a common cosmetic concern. Hyaluronic acid (HA)-based fillers are increasingly popular for minimally invasive facial wrinkle and fold correction. This study aimed to evaluate the efficacy and safety …
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The efficacy of half saline in tumescent liposuction.
Local anesthetic minimally invasive liposuction (LAMS) is a liposuction technique that uses tumescent fluid and involves connecting a syringe to a tiny blunt catheter to remove fat at low pressure. The clinical outcomes of LAMS were compare…
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Needleless laser injector versus needle injection for skin enhancement and rejuvenation effect of dermal filler.
[BACKGROUND AND OBJECTIVES] A needleless laser-induced microjet injector is a novel transdermal drug delivery system that can rapidly inject a very small and precise drug dose into the skin with minimal pain and downtime. In this study, we …
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A Phase 3, Randomized, Multi-center Clinical Trial to Evaluate the Efficacy and Safety of Neu-BoNT/A in Treatment of Primary Axillary Hyperhidrosis.
[BACKGROUND] Botulinum toxin type A is widely used to treat primary axillary hyperhidrosis and has proven to be an effective and safe approach. Onabotulinumtoxin A was approved by the FDA as a treatment for primary axillary hyperhidrosis. T…
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Efficacy and Safety of a New Botulinum Toxin (HU-014) Versus Existing Onabotulinumtoxin A in Subjects With Moderate to Severe Glabellar Lines.
[BACKGROUND] Recently, the safety of a new botulinum toxin (HU-014) was confirmed through animal experiments. The evaluation of the efficacy and safety of this newly introduced botulinum toxin is required considering the risk of adverse eve…
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Phase I/III Clinical Trial to Evaluate the Safety and Efficacy of a New Botulinum Toxin (HU-014) Versus OnabotulinumtoxinA in Subjects With Moderate-to-Severe Crow's Feet Lines.
[BACKGROUND] HU-014, a newly introduced botulinum toxin type A, has not been investigated for its efficacy and safety in crow's feet line (CFL) treatment. [OBJECTIVE] Here, we compared the efficacy and safety of HU-014 and onabotulinumtoxi…
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Efficacy and safety of neuronox for lateral canthal lines: a phase I/III, multicenter, randomized, double-blind, active-controlled study.
[INTRODUCTION] Neuronox has not yet been investigated for its efficacy and safety in the treatment of lateral canthal lines (LCL). [METHODS] This study was a randomized, double-blind, active drug controlled, multicenter, 16 week, Phase I/I…
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Aesthetic Applications of Botulinum Toxin A in Asians: An International, Multidisciplinary, Pan-Asian Consensus.
[BACKGROUND] Botulinum toxin type A remains the most popular nonsurgical aesthetic treatment worldwide. Previous consensus statements have focused on Caucasians and on Koreans as generally representative of Asians. However, indications and …