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Anatomical localization of progenitor cells in human breast tissue reveals enrichment of uncommitted cells within immature lobules.
[INTRODUCTION] Lineage tracing studies in mice have revealed the localization and existence of lineage-restricted mammary epithelial progenitor cells that functionally contribute to expansive growth during puberty and differentiation during…
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Mapping the cellular and molecular heterogeneity of normal and malignant breast tissues and cultured cell lines.
[INTRODUCTION] Normal and neoplastic breast tissues are comprised of heterogeneous populations of epithelial cells involving various degrees of maturation and differentiation. While cultured cell lines have been derived from both normal and…