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LIMS2 regulates lung adenocarcinoma progression and suppresses the activation of cancer-associated fibroblast.
Lung cancer is a highly malignant tumor and prone to recurrence and metastasis. Adenocarcinoma is the most common subtype. LIM zinc finger domain containing 2 (LIMS2) was reported to inhibit growth and metastasis of several tumors, while it…
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[Impact of HIF-1α-expressing Cellular Subpopulations on Lymph Node Metastasis
and Postoperative Recurrence in Non-small Cell Lung Cancer].
[BACKGROUND] Non-small cell lung cancer (NSCLC) is associated with a high rate of postoperative recurrence, and conventional tumor-node-metastasis (TNM) staging does not fully reflect its biological heterogeneity. Hypoxia-inducible factor-1…
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Deep learning model for assessing survival benefits in hepatocellular carcinoma patients undergoing intra-arterial therapies based on proliferative subtype.
The proliferative hepatocellular carcinoma (HCC) subtype is associated with aggressive disease and poor prognosis, yet it remains challenging to identify non-invasively. This retrospective multicenter study developed a multitask deep learni…