SMARCA4 -deficient Non-small Cell Lung Carcinoma Harboring ALK Fusion : A Case Report.
SMARCA4 -deficient non-small cell lung cancers are usually of poor prognosis and associated with smoking-related mutations.
APA
Désage AL, Pointel S, et al. (2026). SMARCA4 -deficient Non-small Cell Lung Carcinoma Harboring ALK Fusion : A Case Report.. Applied immunohistochemistry & molecular morphology : AIMM, 34(1), 38-41. https://doi.org/10.1097/PAI.0000000000001289
MLA
Désage AL, et al.. "SMARCA4 -deficient Non-small Cell Lung Carcinoma Harboring ALK Fusion : A Case Report.." Applied immunohistochemistry & molecular morphology : AIMM, vol. 34, no. 1, 2026, pp. 38-41.
PMID
41055968
Abstract
SMARCA4 -deficient non-small cell lung cancers are usually of poor prognosis and associated with smoking-related mutations. Here, we report the case of a SMARCA4 -deficient non-small cell lung cancer (NSCLC) occurring in a non-smoker female and harboring ALK fusion. Our case highlights for physicians to be especially cautious with molecular biological results in case of SMARCA4 -deficient non-small cell lung cancer occurring in nonsmokers.
MeSH Terms
Humans; Carcinoma, Non-Small-Cell Lung; Female; Lung Neoplasms; Anaplastic Lymphoma Kinase; Nuclear Proteins; Oncogene Proteins, Fusion; Transcription Factors; DNA Helicases; Middle Aged