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Trends of Incidence and Survival of Brain Metastases from Lung Cancer.

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World neurosurgery 📖 저널 OA 13.8% 2021: 0/39 OA 2022: 0/47 OA 2023: 2/31 OA 2024: 7/42 OA 2025: 18/20 OA 2026: 5/20 OA 2021~2026 2026 Vol.205() p. 124636
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유사 논문
P · Population 대상 환자/모집단
환자: advanced lung cancer
I · Intervention 중재 / 시술
추출되지 않음
C · Comparison 대조 / 비교
추출되지 않음
O · Outcome 결과 / 결론
The 1-year survival rate for brain metastases in NSCLC patients increased rapidly (APC: 6.47% [5.43%-7.78%]), whereas in SCLC it increased slowly (APC: 1.86% [-1.08% to 5.06%]). [CONCLUSION] The incidence of brain metastases from lung cancer was decreasing, while the survival time was increasing at different rates.

Zhang C, Zhang H, Jia W

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[BACKGROUND] Brain metastases are common complications in patients with advanced lung cancer.

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↓ .bib ↓ .ris
APA Zhang C, Zhang H, Jia W (2026). Trends of Incidence and Survival of Brain Metastases from Lung Cancer.. World neurosurgery, 205, 124636. https://doi.org/10.1016/j.wneu.2025.124636
MLA Zhang C, et al.. "Trends of Incidence and Survival of Brain Metastases from Lung Cancer.." World neurosurgery, vol. 205, 2026, pp. 124636.
PMID 41238059 ↗

Abstract

[BACKGROUND] Brain metastases are common complications in patients with advanced lung cancer. However, the incidence and prognosis of brain metastases from lung cancer remained vague and outdated. Hence, we sought to analyze trends in the incidence and prognosis of brain metastases from lung cancer from 2010 to 2021.

[METHODS] The Surveillance, Epidemiology, and End Results Program (SEER) registry was queried to identify lung cancer patients with known brain metastases status diagnosed between 2010 and 2021. Age-adjusted incidence and median survival were presented in different demographic groups, and the annual percentage change (APC) was calculated.

[RESULTS] The age-adjusted incidence of brain metastases from non-small cell lung cancer (NSCLC) was 4.60 per 100,000, and was 0.87 per 100,000 from small cell lung cancer (SCLC). The incidence of brain metastases from lung cancer has been decreasing, which was consistent with the declining trend of incidence in primary lung cancer. The proportion of brain metastases was higher in male, younger, and Asian patients with lung cancer. The median survival of brain metastases was 5.0 (4.9-5.1) months in NSCLC and 6.0 (5.8-6.2) months in SCLC. Asian patients with brain metastases from NSCLC exhibited better prognosis (median survival: 11.0 [10.3-11.7] months). The 1-year survival rate for brain metastases in NSCLC patients increased rapidly (APC: 6.47% [5.43%-7.78%]), whereas in SCLC it increased slowly (APC: 1.86% [-1.08% to 5.06%]).

[CONCLUSION] The incidence of brain metastases from lung cancer was decreasing, while the survival time was increasing at different rates.

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🏷️ 같은 키워드 · 무료전문 — 이 논문 MeSH/keyword 기반