← 뒤로

Clinical utility of pleural effusion supernatant cell-free DNA genotyping in previously treated patients with advanced non-small-cell lung cancer and disease progression: a multicenter retrospective study.

1/5 보강

ESMO open 📖 저널 OA 100% 2022~2026 2026 Vol.11(1) p. 106023

PICO 자동 추출 (휴리스틱, conf 3/4)

P · Population 대상 환자/모집단

95 patients who experienced disease progression after at least one line of treatment and underwent pleural effusion cfDNA next-generation sequencing testing.

I · Intervention 중재 / 시술

pleural effusion cfDNA next-generation sequencing testing

C · Comparison 대조 / 비교

추출되지 않음

O · Outcome 결과 / 결론

MYC CNG was associated with a median PFS of 8.5 months versus 25.0 months for those without MYC CNG (HR 8.4, P = 0.0046). [CONCLUSION] CfDNA sampling from pleural effusion is a less invasive and more effective method for genomic profiling in NSCLC with disease progression, offering valuable insights to guide personalized treatment strategies.

Chang SC, Huang CY, Lai YC, Hsieh MS, Ho CC, Yang CY

📖 무료 전문 🟢 PMC 전문 PMC12804021

PubMed ↗ DOI ↗ BibTeX ↓ RIS ↓

Fatal error: Uncaught PDOException: SQLSTATE[42000]: Syntax error or access violation: 1064 You have an error in your SQL syntax; check the manual that corresponds to your MariaDB server version for the right syntax to use near 'JSON)) ORDER BY n_sources DESC LIMIT 6' at line 3 in /home/prsinsight/public_html/app/core/Database.php:33 Stack trace: #0 /home/prsinsight/public_html/app/core/Database.php(33): PDOStatement->execute() #1 /home/prsinsight/public_html/app/models/WikiPage.php(190): App\Core\Database::fetchAll() #2 /home/prsinsight/public_html/app/views/paper/show.php(671): App\Models\WikiPage::backlinksForPaper() #3 /home/prsinsight/public_html/app/core/View.php(32): include('...') #4 /home/prsinsight/public_html/app/core/View.php(15): App\Core\View->capture() #5 /home/prsinsight/public_html/app/core/Controller.php(21): App\Core\View->render() #6 /home/prsinsight/public_html/app/controllers/PaperController.php(372): App\Core\Controller->render() #7 [internal function]: App\Controllers\PaperController->show() #8 /home/prsinsight/public_html/app/core/Router.php(48): call_user_func_array() #9 /home/prsinsight/public_html/app/core/Router.php(34): App\Core\Router->call() #10 /home/prsinsight/public_html/index.php(284): App\Core\Router->dispatch() #11 {main} thrown in /home/prsinsight/public_html/app/core/Database.php on line 33