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Cassia-Derived Natural Flavonoids as Multi-Target Candidates for Lung Cancer Therapy: A Network Pharmacology and Molecular Modeling Study.

1/5 보강

Current medicinal chemistry 📖 저널 OA 2.3% 2021~2026 2026

PICO 자동 추출 (휴리스틱, conf 2/4)

유사 논문

P · Population 대상 환자/모집단

추출되지 않음

I · Intervention 중재 / 시술

100 ns molecular dynamics (MD) simulations with GROMACS to assess binding stability, RMSD, and conformational behavior

C · Comparison 대조 / 비교

추출되지 않음

O · Outcome 결과 / 결론

[CONCLUSION] Cassia-derived flavonoids represent promising multi-target candidates for lung cancer therapy, particularly through modulation of PTGS2, KIT, and XDH. Their favorable interaction profiles and safety predictions warrant further experimental and in vivo validation.

Al Shehri ZS, Rehman A

PubMed ↗ DOI ↗ BibTeX ↓ RIS ↓

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