Feasibility of Latest-Generation Cone-Beam CT for Thoracic Imaging: A Pilot Study.
1/5 보강
PICO 자동 추출 (휴리스틱, conf 2/4)
유사 논문P · Population 대상 환자/모집단
88 patients, current or former smokers, were retrospectively included.
I · Intervention 중재 / 시술
추출되지 않음
C · Comparison 대조 / 비교
추출되지 않음
O · Outcome 결과 / 결론
[CONCLUSION] Low-dose CBCT offers substantial radiation dose reduction without compromising diagnostic confidence or interobserver reliability. CBCT may represent a promising, cost-effective alternative or complement to low-dose CT in preventive lung imaging programs, but prospective studies comparing CBCT to LDCT are warranted.
[BACKGROUND] Lung cancer remains the leading cause of cancer-related death worldwide.
- 표본수 (n) 48
- p-value p<0.001
- p-value p = 0.04
- OR 0.51
- RR 0.99
APA
Bodard S, Segui P, et al. (2026). Feasibility of Latest-Generation Cone-Beam CT for Thoracic Imaging: A Pilot Study.. Academic radiology. https://doi.org/10.1016/j.acra.2025.12.029
MLA
Bodard S, et al.. "Feasibility of Latest-Generation Cone-Beam CT for Thoracic Imaging: A Pilot Study.." Academic radiology, 2026.
PMID
41521115 ↗
Abstract 한글 요약
[BACKGROUND] Lung cancer remains the leading cause of cancer-related death worldwide. Low-dose computed tomography (LDCT) is the current gold standard for screening, but radiation exposure remains a concern. Cone-Beam Computed Tomography (CBCT) offers ultra-low-dose acquisition but has not yet been tested for thoracic screening.
[PURPOSE] To evaluate the feasibility of using a latest-generation CBCT system for thoracic imaging in a lung cancer screening context.
[MATERIALS AND METHODS] 88 patients, current or former smokers, were retrospectively included. They underwent thoracic CBCT (7 G Dual Energy system, NewTom, Italy) between July 2024 and April 2025 at a preventive health center, with either a standard-dose protocol (n = 48) or a low-dose protocol (n = 40). Two board-certified radiologists independently assessed pulmonary findings and image quality. Radiation doses were compared. Statistical analysis included mixed-effects models and interobserver agreement.
[RESULTS] The radiation exposure was significantly lower in the low-dose group, with a median cumulative DLP of 42.8 mGy·cm, compared to 107.7 mGy·cm, representing a 2.5-fold reduction in radiation (p<0.001). Nodule detection occurred in 41% of patients overall. Overall image quality was rated good/excellent in 85% (low-dose) vs 83% (standard-dose); Risk Difference (RD) = +2% [IC95% -12; +16], Risk Ratio (RR) = 1.03. Diagnostic confidence was high in 82% vs 83%; RD = -1% [-14; +12], RR = 0.99. Spatial resolution was slightly lower in the low-dose group (OR = 0.51, p = 0.04). Interobserver agreement for nodule detection was substantial across both groups (κ = 0.73-0.83).
[CONCLUSION] Low-dose CBCT offers substantial radiation dose reduction without compromising diagnostic confidence or interobserver reliability. CBCT may represent a promising, cost-effective alternative or complement to low-dose CT in preventive lung imaging programs, but prospective studies comparing CBCT to LDCT are warranted.
[PURPOSE] To evaluate the feasibility of using a latest-generation CBCT system for thoracic imaging in a lung cancer screening context.
[MATERIALS AND METHODS] 88 patients, current or former smokers, were retrospectively included. They underwent thoracic CBCT (7 G Dual Energy system, NewTom, Italy) between July 2024 and April 2025 at a preventive health center, with either a standard-dose protocol (n = 48) or a low-dose protocol (n = 40). Two board-certified radiologists independently assessed pulmonary findings and image quality. Radiation doses were compared. Statistical analysis included mixed-effects models and interobserver agreement.
[RESULTS] The radiation exposure was significantly lower in the low-dose group, with a median cumulative DLP of 42.8 mGy·cm, compared to 107.7 mGy·cm, representing a 2.5-fold reduction in radiation (p<0.001). Nodule detection occurred in 41% of patients overall. Overall image quality was rated good/excellent in 85% (low-dose) vs 83% (standard-dose); Risk Difference (RD) = +2% [IC95% -12; +16], Risk Ratio (RR) = 1.03. Diagnostic confidence was high in 82% vs 83%; RD = -1% [-14; +12], RR = 0.99. Spatial resolution was slightly lower in the low-dose group (OR = 0.51, p = 0.04). Interobserver agreement for nodule detection was substantial across both groups (κ = 0.73-0.83).
[CONCLUSION] Low-dose CBCT offers substantial radiation dose reduction without compromising diagnostic confidence or interobserver reliability. CBCT may represent a promising, cost-effective alternative or complement to low-dose CT in preventive lung imaging programs, but prospective studies comparing CBCT to LDCT are warranted.
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