Textbook outcome and long-term survival after pulmonary resection for non-small cell lung cancer: a retrospective cohort study.
코호트
1/5 보강
PICO 자동 추출 (휴리스틱, conf 2/4)
유사 논문P · Population 대상 환자/모집단
731 patients, 163 (22.
I · Intervention 중재 / 시술
추출되지 않음
C · Comparison 대조 / 비교
추출되지 않음
O · Outcome 결과 / 결론
[TRIAL REGISTRATION] This study was retrospectively registered in the Australian-New Zealand Clinical Trials Registry (ACTRN12625000913471). [SUPPLEMENTARY INFORMATION] The online version contains supplementary material available at 10.1186/s12957-026-04195-9.
[BACKGROUND] Textbook outcome is a composite measure reflecting an ideal perioperative course by integrating multiple care-quality indicators.
- 95% CI 0.36–0.77
- 연구 설계 cohort study
APA
Raykateeraroj N, Chu F, et al. (2026). Textbook outcome and long-term survival after pulmonary resection for non-small cell lung cancer: a retrospective cohort study.. World journal of surgical oncology, 24(1), 73. https://doi.org/10.1186/s12957-026-04195-9
MLA
Raykateeraroj N, et al.. "Textbook outcome and long-term survival after pulmonary resection for non-small cell lung cancer: a retrospective cohort study.." World journal of surgical oncology, vol. 24, no. 1, 2026, pp. 73.
PMID
41540440
Abstract
[BACKGROUND] Textbook outcome is a composite measure reflecting an ideal perioperative course by integrating multiple care-quality indicators. While its use has been reported internationally for non-small cell lung cancer (NSCLC) resection, it has not previously been evaluated in the Australian setting. This study aimed to determine the proportion of patients achieving a textbook outcome after NSCLC resection, identify the components that most commonly prevented its attainment, and evaluate its association with long-term overall survival.
[METHODS] A retrospective cohort study was conducted of adults undergoing lung resection for primary NSCLC at a tertiary Australian centre (2011–2023). Textbook outcome was defined according to the Dutch Lung Cancer Audit–Surgery criteria, requiring negative margins, complete lymph node dissection, absence of major complications, no 30-day mortality or reintervention, no prolonged ICU/high-dependency stay, no prolonged hospitalisation, and no readmission. Multivariable logistic regression identified predictors of textbook outcome, and Kaplan–Meier analysis was used to assess long-term survival.
[RESULTS] Of 731 patients, 163 (22.3%) met all textbook outcome criteria. Failure to achieve the composite outcome was most commonly caused by incomplete lymph node dissection (67.6%), reintervention (22.5%), major complications (20.2%), or prolonged stay (13.2%). Male sex (OR 0.53, 95% CI 0.36–0.77) and open surgery (OR 0.54, 95% CI 0.35–0.83) were associated with lower odds of meeting the criteria, while carcinoid histology increased the odds (OR 1.91, 95% CI 1.04–3.45). Patients who met the textbook outcome criteria had higher survival (5-year: 89.7% vs. 70.8%; 10-year: 82.0% vs. 60.7%; log-rank 0.001).
[CONCLUSION] Textbook outcome was achieved in approximately one-fifth of patients and was strongly associated with improved long-term survival. Enhancing lymph node dissection and wider adoption of minimally invasive surgery may help increase textbook outcome rates and represents a potential focus for future quality-improvement initiatives.
[TRIAL REGISTRATION] This study was retrospectively registered in the Australian-New Zealand Clinical Trials Registry (ACTRN12625000913471).
[SUPPLEMENTARY INFORMATION] The online version contains supplementary material available at 10.1186/s12957-026-04195-9.
[METHODS] A retrospective cohort study was conducted of adults undergoing lung resection for primary NSCLC at a tertiary Australian centre (2011–2023). Textbook outcome was defined according to the Dutch Lung Cancer Audit–Surgery criteria, requiring negative margins, complete lymph node dissection, absence of major complications, no 30-day mortality or reintervention, no prolonged ICU/high-dependency stay, no prolonged hospitalisation, and no readmission. Multivariable logistic regression identified predictors of textbook outcome, and Kaplan–Meier analysis was used to assess long-term survival.
[RESULTS] Of 731 patients, 163 (22.3%) met all textbook outcome criteria. Failure to achieve the composite outcome was most commonly caused by incomplete lymph node dissection (67.6%), reintervention (22.5%), major complications (20.2%), or prolonged stay (13.2%). Male sex (OR 0.53, 95% CI 0.36–0.77) and open surgery (OR 0.54, 95% CI 0.35–0.83) were associated with lower odds of meeting the criteria, while carcinoid histology increased the odds (OR 1.91, 95% CI 1.04–3.45). Patients who met the textbook outcome criteria had higher survival (5-year: 89.7% vs. 70.8%; 10-year: 82.0% vs. 60.7%; log-rank 0.001).
[CONCLUSION] Textbook outcome was achieved in approximately one-fifth of patients and was strongly associated with improved long-term survival. Enhancing lymph node dissection and wider adoption of minimally invasive surgery may help increase textbook outcome rates and represents a potential focus for future quality-improvement initiatives.
[TRIAL REGISTRATION] This study was retrospectively registered in the Australian-New Zealand Clinical Trials Registry (ACTRN12625000913471).
[SUPPLEMENTARY INFORMATION] The online version contains supplementary material available at 10.1186/s12957-026-04195-9.