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Ceritinib efficacy in SMARCA4-deficient NSCLC harboring novel CTNND2 ALK/EML4-ALK fusion: case report.

증례보고 1/5 보강
Frontiers in oncology 📖 저널 OA 100% 2021: 15/15 OA 2022: 98/98 OA 2023: 60/60 OA 2024: 189/189 OA 2025: 1004/1004 OA 2026: 620/620 OA 2021~2026 2026 Vol.16() p. 1680523
Retraction 확인
출처

PICO 자동 추출 (휴리스틱, conf 2/4)

유사 논문
P · Population 대상 환자/모집단
추출되지 않음
I · Intervention 중재 / 시술
ceritinib (750 mg/day)
C · Comparison 대조 / 비교
추출되지 않음
O · Outcome 결과 / 결론
After 3 months, targeted lesions regressed significantly, and progression-free survival exceeded 24 months with ongoing response. This demonstrates efficacy of the ALK inhibitor ceritinib in ALK-rearranged SMARCA4-dNSCLC and underscores the clinical value of genomic-guided therapy.

Fu Z, Huang G, Xie J, Luo L, Ren Q, He H


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