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Current diagnosis, epidemiology, and management of interstitial lung abnormalities.

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Frontiers in medicine 📖 저널 OA 100% 2021: 5/5 OA 2022: 14/14 OA 2023: 10/10 OA 2024: 14/14 OA 2025: 175/175 OA 2026: 119/119 OA 2021~2026 2026 Vol.13() p. 1732754
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Moua T, Baqir M, Tzilas V, Ryu JH

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Interstitial lung abnormalities (ILAs) are incidental nondependent radiologic findings that may portend early or future interstitial lung disease (ILD), but do not meet specific criteria at the time o

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APA Moua T, Baqir M, et al. (2026). Current diagnosis, epidemiology, and management of interstitial lung abnormalities.. Frontiers in medicine, 13, 1732754. https://doi.org/10.3389/fmed.2026.1732754
MLA Moua T, et al.. "Current diagnosis, epidemiology, and management of interstitial lung abnormalities.." Frontiers in medicine, vol. 13, 2026, pp. 1732754.
PMID 41728627 ↗

Abstract

Interstitial lung abnormalities (ILAs) are incidental nondependent radiologic findings that may portend early or future interstitial lung disease (ILD), but do not meet specific criteria at the time of presentation. They are subclinical by definition and found more commonly in older ever-smokers undergoing computed tomography (CT) imaging for other indications, including cardiac or lung cancer screening programs. As ILA prevalence increases, driven by an aging population and heightened awareness in younger patients, understanding risk factors for their development and progression has gained recent interest, particularly for optimizing subsequent ILD outcomes. This narrative review summarizes current ILA definitions, epidemiology, risk stratification, and management, while highlighting current challenges and knowledge gaps.

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