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Intrapleural anti-PD-1 antibody for the treatment of advanced non-small cell lung cancer with malignant pleural effusion: a prospective, single-arm, single-center, phase I trial.

3/5 보강
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 📖 저널 OA 14.8% 2022: 0/2 OA 2023: 0/3 OA 2024: 4/7 OA 2025: 7/46 OA 2026: 31/223 OA 2022~2026 2026 Vol.28(4) p. 1246-1256 cited 1 Pleural and Pulmonary Diseases
TL;DR Intrapleural injection of anti-PD-1 antibody demonstrates promising efficacy and a tolerable safety profile as a novel therapeutic strategy for managing MPE in advanced NSCLC.
Retraction 확인
출처
PubMed DOI OpenAlex Semantic 마지막 보강 2026-05-01

PICO 자동 추출 (휴리스틱, conf 3/4)

유사 논문
P · Population 대상 환자/모집단
16 patients, the proportion of participants with successful pleurodesis at day 35 was 75.
I · Intervention 중재 / 시술
a single intrapleural dose of 100 mg of sintilimab
C · Comparison 대조 / 비교
추출되지 않음
O · Outcome 결과 / 결론
[CONCLUSIONS] Intrapleural injection of anti-PD-1 antibody demonstrates promising efficacy and a tolerable safety profile as a novel therapeutic strategy for managing MPE in advanced NSCLC. [TRIAL REGISTRATION] This trial was registered with the Chinese Clinical Trial Registry (identifier: ChiCTR2400087743).
OpenAlex 토픽 · Pleural and Pulmonary Diseases Cancer Immunotherapy and Biomarkers Occupational and environmental lung diseases

Cui Y, Wu Q, Hao Y, Wu G, Cheng Q, Song X


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