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Chromosome 15q15 Deletion Drives Brain Metastasis in NSCLC.

2/5 보강

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 📖 저널 OA 12.2% 2022~2026 2026 Vol.21(4) p. 103511 Neuroblastoma Research and Treatment

TL;DR The 15q15 deletion promotes BM development through aberrant MYC signaling and the subsequent reprogramming of carbohydrate metabolism and the subsequent reprogramming of carbohydrate metabolism.

PICO 자동 추출 (휴리스틱, conf 2/4)

유사 논문

P · Population 대상 환자/모집단

환자: BM than in those without this deletion (73% versus 39%, p = 0

I · Intervention 중재 / 시술

추출되지 않음

C · Comparison 대조 / 비교

추출되지 않음

O · Outcome 결과 / 결론

NSCLC cell lines harboring the 15q15 deletion were selectively sensitive to elesclomol, an OXPHOS inhibitor. [CONCLUSIONS] The 15q15 deletion promotes BM development through aberrant MYC signaling and the subsequent reprogramming of carbohydrate metabolism.

OpenAlex 토픽 · Neuroblastoma Research and Treatments Neurogenesis and neuroplasticity mechanisms Genomic variations and chromosomal abnormalities

Miyakoshi J, Shiraishi K, Mochizuki A, Tateishi A, Shimoda-Igawa Y, Torasawa M

PubMed ↗ DOI ↗ BibTeX ↓ RIS ↓

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