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Empirical Osimertinib as a Second-Line Treatment Is a Viable Option Following First- and Second-Generation TKI Therapy With Unknown EGFR Status in Treated Non-Small Cell Lung Cancer: A Retrospective Study.

2/5 보강

Cancer medicine 📖 저널 OA 96.3% 2022~2026 2026 Vol.15(5) p. e71881 OA Lung Cancer Treatments and Mutations

PICO 자동 추출 (휴리스틱, conf 3/4)

P · Population 대상 환자/모집단

160 patients with EGFR-mutated lung adenocarcinoma at clinical stages IIIB-IVB received first- or second-generation EGFR-TKI frontline therapy.

I · Intervention 중재 / 시술

first- or second-generation EGFR-TKI frontline therapy

C · Comparison 대조 / 비교

추출되지 않음

O · Outcome 결과 / 결론

The RR of 42.7% and median ToT of 5.6 months appear consistent with historical outcomes reported for second-line platinum-based chemotherapy. Osimertinib provides an additional treatment line for patients whose tumors are difficult to access and have an unknown T790M status, making it a valuable treatment option for these patients.

OpenAlex 토픽 · Lung Cancer Treatments and Mutations Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis Lung Cancer Diagnosis and Treatment

Lin MH, Chu KA, Chen CF, Jiang YC, Hong WC, Hung MY

📖 무료 전문 🟢 PMC 전문 PMC13109614 🔓 OA PDF oa

PubMed ↗ DOI ↗ BibTeX ↓ RIS ↓

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