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Cardiopulmonary complications in cancer: from tumour pathogenesis to treatment-induced toxicity and clinical management.

Postgraduate medical journal 2025 Vol.102(1203) p. 3-16

Mao Z, Wang X, Chen S, Zhang C, Chen Y, Deng S, Liu Y, Xu X, Zhang T, Liao J, He Y, Wang W, Zeng T, Song Y

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This paper provides a comprehensive overview of cardiopulmonary events associated with the occurrence, development, and treatment of tumours, serving as a valuable resource for the clinical management

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APA Mao Z, Wang X, et al. (2025). Cardiopulmonary complications in cancer: from tumour pathogenesis to treatment-induced toxicity and clinical management.. Postgraduate medical journal, 102(1203), 3-16. https://doi.org/10.1093/postmj/qgaf070
MLA Mao Z, et al.. "Cardiopulmonary complications in cancer: from tumour pathogenesis to treatment-induced toxicity and clinical management.." Postgraduate medical journal, vol. 102, no. 1203, 2025, pp. 3-16.
PMID 40448347

Abstract

This paper provides a comprehensive overview of cardiopulmonary events associated with the occurrence, development, and treatment of tumours, serving as a valuable resource for the clinical management of cancer patients. It explores the complex relationship between the heart and lungs, collectively discussing the cardiopulmonary implications linked to tumours. Common risk factors that connect tumours with cardiac and pulmonary conditions are delineated, highlighting their direct and indirect correlations. Additionally, the paper addresses the cardiopulmonary disorders and symptoms resulting from tumour progression and their subsequent manifestations. The final section focuses on the cardiopulmonary repercussions of various tumour treatments, including chemotherapy, targeted therapy, radiation therapy, and immunotherapy, elaborating on their associated cardiopulmonary effects. Effective management of aggressive proliferative diseases, such as tumours, requires selecting appropriate treatment modalities that balance therapeutic efficacy with vigilant monitoring of cardiopulmonary function and thorough assessment of treatment outcomes and related side effects.

MeSH Terms

Humans; Neoplasms; Antineoplastic Agents; Lung Diseases; Heart Diseases; Radiotherapy; Immunotherapy; Cardiotoxicity; Risk Factors

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