Anti-cancer Potential of Scopoletin Derivatives Across Diverse Cancer Cell Lines: A Comprehensive Review.

Scopoletin, a naturally occurring coumarin derivative, has garnered significant attention for its diverse pharmacological properties, including potent anticancer activity. This review provides a comprehensive examination of scopoletin's anticancer effects across a wide range of tumor cell lines. The paper explores its modulation of apoptotic pathways, inhibition concentration (IC) of cancer cell proliferation, and suppression of metastasis and angiogenesis. Additionally, the review discusses the role of scopoletin in regulating oxidative stress, inflammation, and cell cycle arrest in cancer cells. A detailed analysis of and studies highlights its efficacy, specificity, and potential for synergistic effects when used in combination with conventional chemotherapeutics. Hence, this comprehensive review aims to provide a foundation for future research and development of scopoletin as a promising anticancer agent.