A 21-Year-Old Female with Invasive Breast Cancer within a Benign Phyllodes Tumor.
[INTRODUCTION] Although breast cancer occurring within a phyllodes tumor (PT) has been reported, it is extremely rare in young patients.
APA
Yoneda H, Shimizu Y, et al. (2026). A 21-Year-Old Female with Invasive Breast Cancer within a Benign Phyllodes Tumor.. Surgical case reports, 12(1). https://doi.org/10.70352/scrj.cr.25-0503
MLA
Yoneda H, et al.. "A 21-Year-Old Female with Invasive Breast Cancer within a Benign Phyllodes Tumor.." Surgical case reports, vol. 12, no. 1, 2026.
PMID
41585001
Abstract
[INTRODUCTION] Although breast cancer occurring within a phyllodes tumor (PT) has been reported, it is extremely rare in young patients. Herein, we describe a case of breast cancer complicated by a PT in a 21-year-old female.
[CASE PRESENTATION] A 21-year-old female was referred to our hospital with a rapidly growing breast mass and suspected PT. Mammography revealed a well-defined, high-density mass. Ultrasonography revealed a blood-flow-rich hypoechoic mass with multiple slit structures, and MRI revealed a heterogeneous high signal on T2 weighted image with some diffusion restriction. A core needle biopsy revealed fibroepithelial lesions, and the lack of stromal changes suggested a high possibility of fibroadenoma. Based on the clinical and imaging findings, we considered the possibility of the PT being more than borderline malignant and planned tumor resection with a safety margin. The postoperative pathology revealed a benign PT complicated by invasive ductal carcinoma, with a predominance of intraductal carcinoma.
[CONCLUSIONS] We report the case of a 21-year-old female with breast cancer occurring within a PT. The presence of cancer was difficult to predict preoperatively based on the patient's young age and imaging findings.
[CASE PRESENTATION] A 21-year-old female was referred to our hospital with a rapidly growing breast mass and suspected PT. Mammography revealed a well-defined, high-density mass. Ultrasonography revealed a blood-flow-rich hypoechoic mass with multiple slit structures, and MRI revealed a heterogeneous high signal on T2 weighted image with some diffusion restriction. A core needle biopsy revealed fibroepithelial lesions, and the lack of stromal changes suggested a high possibility of fibroadenoma. Based on the clinical and imaging findings, we considered the possibility of the PT being more than borderline malignant and planned tumor resection with a safety margin. The postoperative pathology revealed a benign PT complicated by invasive ductal carcinoma, with a predominance of intraductal carcinoma.
[CONCLUSIONS] We report the case of a 21-year-old female with breast cancer occurring within a PT. The presence of cancer was difficult to predict preoperatively based on the patient's young age and imaging findings.