Glucose metabolism in anterior pituitary adenomas.
1/5 보강
PICO 자동 추출 (휴리스틱, conf 2/4)
유사 논문P · Population 대상 환자/모집단
환자: secretory pituitary adenomas
I · Intervention 중재 / 시술
추출되지 않음
C · Comparison 대조 / 비교
추출되지 않음
O · Outcome 결과 / 결론
Excessive TSH leads to increased T3 and T4 production, which in turn stimulate glucose uptake in muscle and enhance both glycolysis and gluconeogenesis. This review summarizes the current understanding of how hormone hypersecretion in pituitary adenomas contributes to glucose metabolism dysregulation.
ℹ️ 이 논문은 무료 전문이 아직 없습니다. 코퍼스 전체의 43.8%는 무료 가능 (통계 →) · 🏥 기관 EZproxy로 시도
Glucose metabolism alterations are frequently observed in patients with secretory pituitary adenomas.
APA
Hernández-Brito V, Casco-Morales SL, Vega-Rosas A (2026). Glucose metabolism in anterior pituitary adenomas.. Clinica chimica acta; international journal of clinical chemistry, 578, 120587. https://doi.org/10.1016/j.cca.2025.120587
MLA
Hernández-Brito V, et al.. "Glucose metabolism in anterior pituitary adenomas.." Clinica chimica acta; international journal of clinical chemistry, vol. 578, 2026, pp. 120587.
PMID
40912478 ↗
Abstract 한글 요약
Glucose metabolism alterations are frequently observed in patients with secretory pituitary adenomas. The most commonly secreted hormones in these tumors include prolactin, growth hormone (GH), adrenocorticotropic hormone (ACTH), and thyroid-stimulating hormone (TSH), all of which can disrupt glucose homeostasis through distinct pathophysiological mechanisms. Prolactin stimulates pancreatic β-cell proliferation, enhances insulin gene transcription, increases intracellular insulin content, and augments glucose-induced insulin secretion. GH promotes lipolysis and hepatic glucose production while impairing peripheral glucose uptake, contributing to insulin resistance. ACTH, via excess glucocorticoids, reduces GLUT-4 translocation, enhances gluconeogenesis and proteolysis, and inhibits glycogen synthesis. Excessive TSH leads to increased T3 and T4 production, which in turn stimulate glucose uptake in muscle and enhance both glycolysis and gluconeogenesis. This review summarizes the current understanding of how hormone hypersecretion in pituitary adenomas contributes to glucose metabolism dysregulation.
🏷️ 키워드 / MeSH 📖 같은 키워드 OA만
🏷️ 같은 키워드 · 무료전문 — 이 논문 MeSH/keyword 기반
- A Phase I Study of Hydroxychloroquine and Suba-Itraconazole in Men with Biochemical Relapse of Prostate Cancer (HITMAN-PC): Dose Escalation Results.
- Self-management of male urinary symptoms: qualitative findings from a primary care trial.
- Clinical and Liquid Biomarkers of 20-Year Prostate Cancer Risk in Men Aged 45 to 70 Years.
- Diagnostic accuracy of Ga-PSMA PET/CT versus multiparametric MRI for preoperative pelvic invasion in the patients with prostate cancer.
- Association of patient health education with the postoperative health related quality of life in low- intermediate recurrence risk differentiated thyroid cancer patients.
- Early local immune activation following intra-operative radiotherapy in human breast tissue.