The Multi-pathway Mechanism and Co-delivery System of Oleanolic Acid Derivatives in Reversing Chemotherapy Resistance in Breast Cancer.
1/5 보강
Breast cancer threatens the health of women worldwide.
APA
Yang K, Li Y, et al. (2026). The Multi-pathway Mechanism and Co-delivery System of Oleanolic Acid Derivatives in Reversing Chemotherapy Resistance in Breast Cancer.. Anti-cancer agents in medicinal chemistry. https://doi.org/10.2174/0118715206397143251021064739
MLA
Yang K, et al.. "The Multi-pathway Mechanism and Co-delivery System of Oleanolic Acid Derivatives in Reversing Chemotherapy Resistance in Breast Cancer.." Anti-cancer agents in medicinal chemistry, 2026.
PMID
41503911 ↗
Abstract 한글 요약
Breast cancer threatens the health of women worldwide. However, the use of chemotherapy for breast cancer is prone to generating side effects and drug resistance. Therefore, identifying natural compounds with anticancer activity is a better solution to the problem of drug resistance. Oleanolic acid (OA), a kind of pentacyclic triterpenoid, is widely studied and used in the field of oncology. It has biological activity against breast cancer and has few side effects on normal cells. OA can be used as a frame for chemical modification to synthesize new compounds for the development of new drugs. At present, some OA derivatives with anti-breast cancer biological activity have been proven clinically, while others have emerged as candidates. This review aims to provide a comprehensive understanding of the mechanisms of oleanolic acid and its derivatives on breast cancer from previous studies.
🏷️ 키워드 / MeSH 📖 같은 키워드 OA만
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