Emerging Biomarkers for Managing Barrett's Esophagus.
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Comparative analyses of normal esophageal tissue, Barrett's Esophagus (BE), and esophageal adenocarcinoma have identified distinctive molecular alterations in genomic DNA, epigenetics, non-coding RNA,
APA
Rojanasopondist P, Kaz A, et al. (2026). Emerging Biomarkers for Managing Barrett's Esophagus.. Gastrointestinal endoscopy clinics of North America, 36(1), 149-170. https://doi.org/10.1016/j.giec.2025.05.005
MLA
Rojanasopondist P, et al.. "Emerging Biomarkers for Managing Barrett's Esophagus.." Gastrointestinal endoscopy clinics of North America, vol. 36, no. 1, 2026, pp. 149-170.
PMID
41260765 ↗
Abstract 한글 요약
Comparative analyses of normal esophageal tissue, Barrett's Esophagus (BE), and esophageal adenocarcinoma have identified distinctive molecular alterations in genomic DNA, epigenetics, non-coding RNA, and proteins that have shown promise as disease-specific biomarkers. Some of the best characterized and promising biomarkers for managing BE are multi-target esophageal cytology DNA assays based on methylated-DNA and immunohistochemical staining of Trefoil factor 3. Additional biomarkers including microRNA, measures of genomic instability, mixed-method panels, and other novel biomarkers (e.g. volatile organic compounds and saliva microbiome) remain in early development and will need further validation in large, prospective studies prior to clinical use.
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