Organ preservation in rectal cancer: Clinical basis of the watch-and-wait strategy.
기술보고
1/5 보강
PICO 자동 추출 (휴리스틱, conf 2/4)
유사 논문P · Population 대상 환자/모집단
환자: rectal cancer following neoadjuvant therapy
I · Intervention 중재 / 시술
추출되지 않음
C · Comparison 대조 / 비교
추출되지 않음
O · Outcome 결과 / 결론
However, this strategy requires careful patient selection, standardised re-evaluation protocols, and intensive follow-up in specialised centres. In summary, W&W has become a valid and safe alternative to surgical treatment in selected patients with rectal cancer following neoadjuvant therapy.
Locally advanced rectal cancer has traditionally been treated with neoadjuvant chemoradiotherapy, followed by total mesorectal excision (TME)-a technique that is effective but associated with high mor
APA
Jimenez-Rodriguez RM, Aguilar-Del-Castillo F, et al. (2026). Organ preservation in rectal cancer: Clinical basis of the watch-and-wait strategy.. Cirugia espanola, 104(1), 800248. https://doi.org/10.1016/j.cireng.2025.800248
MLA
Jimenez-Rodriguez RM, et al.. "Organ preservation in rectal cancer: Clinical basis of the watch-and-wait strategy.." Cirugia espanola, vol. 104, no. 1, 2026, pp. 800248.
PMID
41276254 ↗
Abstract 한글 요약
Locally advanced rectal cancer has traditionally been treated with neoadjuvant chemoradiotherapy, followed by total mesorectal excision (TME)-a technique that is effective but associated with high morbidity and functional impairment. The identification of patients with a clinical complete response (cCR) after treatment has driven the adoption of the "Watch-and-Wait" (W&W) strategy, aimed at avoiding surgery without compromising oncologic safety. Current evidence, drawn from international series, multicentre records, and clinical trials, supports the view that W&W offers overall survival and disease-free survival rates comparable to those of radical surgery, with clear advantages in organ preservation and quality of life. However, this strategy requires careful patient selection, standardised re-evaluation protocols, and intensive follow-up in specialised centres. In summary, W&W has become a valid and safe alternative to surgical treatment in selected patients with rectal cancer following neoadjuvant therapy.
🏷️ 키워드 / MeSH 📖 같은 키워드 OA만
- Humans
- Rectal Neoplasms
- Organ Sparing Treatments
- Neoadjuvant Therapy
- Watchful Waiting
- Quality of Life
- Organ Preservation
- Disease-Free Survival
- Cáncer de recto
- Escisión total del mesorrecto
- Oncological survival
- Organ preservation treatments
- Rectal cancer
- Supervivencia oncológica
- Total mesolectal excision
- Tratamientos de preservación de órganos
- Watch-and-wait
🏷️ 같은 키워드 · 무료전문 — 이 논문 MeSH/keyword 기반
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