[Cardiac side effects of immunotherapy : Role of imaging in immuno-oncology].
1/5 보강
[BACKGROUND] Immunotherapies have become an integral part of modern oncology.
APA
Aziz-Safaie T, Beissel LD, et al. (2026). [Cardiac side effects of immunotherapy : Role of imaging in immuno-oncology].. Radiologie (Heidelberg, Germany), 66(1), 41-46. https://doi.org/10.1007/s00117-025-01550-x
MLA
Aziz-Safaie T, et al.. "[Cardiac side effects of immunotherapy : Role of imaging in immuno-oncology].." Radiologie (Heidelberg, Germany), vol. 66, no. 1, 2026, pp. 41-46.
PMID
41400822 ↗
Abstract 한글 요약
[BACKGROUND] Immunotherapies have become an integral part of modern oncology. Despite their therapeutic success, they are associated with cardiotoxic side effects that require early detection. Cardiac magnetic resonance imaging (CMR), as a noninvasive modality, enables precise tissue characterization of immune-mediated myocardial injury.
[OBJECTIVES] To present cardiotoxic effects of immunotherapies and the role of CMR in diagnosis and risk stratification.
[MATERIALS AND METHODS] Current scientific literature and clinical guidelines were reviewed regarding the incidence, pathophysiology, and imaging-based diagnosis of cardiotoxic effects related to immunotherapies.
[RESULTS] Myocarditis associated with immune checkpoint inhibitors is rare but linked to high mortality. Chimeric antigen receptor (CAR)-T-related cardiotoxicity often occurs in the context of cytokine release syndrome and can be assessed by CMR with respect to both functional and structural myocardial changes.
[CONCLUSION] CMR plays a central role in the noninvasive diagnosis of immunotherapy-related cardiotoxicity and is essential for clinical decision-making and risk stratification.
[OBJECTIVES] To present cardiotoxic effects of immunotherapies and the role of CMR in diagnosis and risk stratification.
[MATERIALS AND METHODS] Current scientific literature and clinical guidelines were reviewed regarding the incidence, pathophysiology, and imaging-based diagnosis of cardiotoxic effects related to immunotherapies.
[RESULTS] Myocarditis associated with immune checkpoint inhibitors is rare but linked to high mortality. Chimeric antigen receptor (CAR)-T-related cardiotoxicity often occurs in the context of cytokine release syndrome and can be assessed by CMR with respect to both functional and structural myocardial changes.
[CONCLUSION] CMR plays a central role in the noninvasive diagnosis of immunotherapy-related cardiotoxicity and is essential for clinical decision-making and risk stratification.
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