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Efficacy and safety of immune checkpoint inhibitors and mTOR inhibitors as targeted therapy for glioblastoma: A systematic review and meta-analysis of randomized clinical trials.

메타분석 1/5 보강
Neurosurgical review 📖 저널 OA 24.8% 2021: 4/18 OA 2022: 4/17 OA 2023: 1/7 OA 2024: 5/20 OA 2025: 4/25 OA 2026: 12/30 OA 2021~2026 2026 Vol.49(1) p. 95
Retraction 확인
출처

PICO 자동 추출 (휴리스틱, conf 2/4)

유사 논문
P · Population 대상 환자/모집단
130 patients were included (12 on ICIs, 9 on mTOR inhibitors).
I · Intervention 중재 / 시술
추출되지 않음
C · Comparison 대조 / 비교
추출되지 않음
O · Outcome 결과 / 결론
Neither ICIs nor mTOR inhibitors consistently improved survival in unselected GB populations. However, tailored approaches based on molecular features or delivery methods may offer benefits and should be further investigated.

Gómez EG, Morales MAM, San-Juan D, Romero-Valencia J, Mendez DLR, Hernandez DOL


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