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Healthcare impact and surgical safety of endoscopic mastectomy in women with breast cancer or high-risk. Preliminary outcomes from the VideoBreast-24 trial.

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Cirugia espanola 📖 저널 OA 0% 2026 Vol.104(2) p. 800290
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Acea-Nebril B, García-Novoa A, Sierra S, Santos L, Cereijo-Garea C

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[INTRODUCTION] Skin and nipple-sparing mastectomy (NSSM) with immediate reconstruction has become the standard treatment for women requiring a mastectomy.

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APA Acea-Nebril B, García-Novoa A, et al. (2026). Healthcare impact and surgical safety of endoscopic mastectomy in women with breast cancer or high-risk. Preliminary outcomes from the VideoBreast-24 trial.. Cirugia espanola, 104(2), 800290. https://doi.org/10.1016/j.cireng.2026.800290
MLA Acea-Nebril B, et al.. "Healthcare impact and surgical safety of endoscopic mastectomy in women with breast cancer or high-risk. Preliminary outcomes from the VideoBreast-24 trial.." Cirugia espanola, vol. 104, no. 2, 2026, pp. 800290.
PMID 41621478

Abstract

[INTRODUCTION] Skin and nipple-sparing mastectomy (NSSM) with immediate reconstruction has become the standard treatment for women requiring a mastectomy. The objective of this article is to describe endoscopic mastectomy (E-NSSM) and analyze the initial results after its implementation in terms of care impact and post-surgical complications.

[PATIENT AND METHODS] Preliminary results of the VideoBreast-24 in terms of safety and feasibility of the technique. VideoBreast-24 is a non-inferiority study that compares MPPP-E with immediate reconstruction with a polyurethane implant versus skin-sparing or skin-and-nipple mastectomy using the open technique (O-NSSM) performed within the framework of the PreQ-20 study.

[RESULTS] 60 E-NSSM were performed on 42 women, 92.9% of whom were oncological patients. The average surgery time was 213.7 min. The average implant volume is 322cc, with the largest volume being 545cc. There were no implant losses.

[CONCLUSIONS] Endoscopic mastectomy is a technique with a low incidence of postoperative complications, surgical reintervention and readmission. Surgical time is longer than that of open mastectomy, although it can be optimized once the learning curve has passed.

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