[Preventive Surgery for Hereditary Gastric Cancer].
Hereditary diffuse gastric cancer (HDGC) caused by disease-causing variant in or and familial adenomatous polyposis (FAP, disease-causing variants in ) require individualised cancer prevention strat
APA
Lee H, Stein H, et al. (2026). [Preventive Surgery for Hereditary Gastric Cancer].. Zentralblatt fur Chirurgie, 151(1), 27-33. https://doi.org/10.1055/a-2731-7680
MLA
Lee H, et al.. "[Preventive Surgery for Hereditary Gastric Cancer].." Zentralblatt fur Chirurgie, vol. 151, no. 1, 2026, pp. 27-33.
PMID
41297892
Abstract
Hereditary diffuse gastric cancer (HDGC) caused by disease-causing variant in or and familial adenomatous polyposis (FAP, disease-causing variants in ) require individualised cancer prevention strategies. In HDGC, prophylactic total gastrectomy is often recommended, whereas in FAP, endoscopic surveillance with interventions plays a central role. The choice of reconstruction (Roux-en-Y, jejunal interposition, double-tract) affects both duodenal accessibility and quality of life. Decisions between surveillance and surgery should be made individually, balancing cancer risk and postoperative quality of life.
MeSH Terms
Humans; Stomach Neoplasms; Adenomatous Polyposis Coli; Gastrectomy; Prophylactic Surgical Procedures; Quality of Life
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