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Magnetic resonance imaging findings of non-mass enhancements in the breast and their association with malignancy.

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Medicine 2026 Vol.105(8) p. e47854
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Guven F, Ozturk ME

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Our aim is to investigate the relationship between the MRI (Magnetic Resonance Imaging) features of non-mass enhancement (NME) lesions and malignancy.

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APA Guven F, Ozturk ME (2026). Magnetic resonance imaging findings of non-mass enhancements in the breast and their association with malignancy.. Medicine, 105(8), e47854. https://doi.org/10.1097/MD.0000000000047854
MLA Guven F, et al.. "Magnetic resonance imaging findings of non-mass enhancements in the breast and their association with malignancy.." Medicine, vol. 105, no. 8, 2026, pp. e47854.
PMID 41731785

Abstract

Our aim is to investigate the relationship between the MRI (Magnetic Resonance Imaging) features of non-mass enhancement (NME) lesions and malignancy. MRI findings of 200 and 2 NME lesions were retrospectively evaluated. Age, family history of breast cancer, lesion pathology results, and follow-up durations of the patients were obtained from medical records. Based on follow-up findings and pathology results, the lesions were classified into 3 groups as benign, high-risk, and malignant. The association between these groups and MRI features was analyzed statistically. Segmental (48.4%) and diffuse (85.7%) distribution patterns, as well as clumped (51.5%) and clustered ring (100%) enhancement patterns of NME lesions, were found to be associated with malignant lesions. According to the time-intensity curve, a Type 3 curve was associated with malignant lesions in 84.6% of cases. When evaluating the number of dynamic curves, lesions with multiple curves were considered malignant in 29.2% of cases. Regarding apparent diffusion coefficient (ADC) values, malignant and high-risk lesions had significantly lower ADC values compared to benign lesions. In this study, segmental and diffuse distribution patterns, clumped and clustered ring enhancement, Type 3 curve, and low ADC values were found to be associated with malignant lesions.

MeSH Terms

Humans; Female; Breast Neoplasms; Retrospective Studies; Middle Aged; Adult; Magnetic Resonance Imaging; Breast; Aged

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