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A Rare Clown Nose Manifestation of Metastatic Eccrine Porocarcinoma: Case Study and Review of the Literature.

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The American Journal of dermatopathology 📖 저널 OA 2.5% 2026 Vol.48(2) p. 125-131
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Wang QX, Li FZ, Zhang CK, Fang S

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The "clown nose" is a rare clinical presentation characterized by reddish-brown nodular lesions localized to the nasal tip.

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APA Wang QX, Li FZ, et al. (2026). A Rare Clown Nose Manifestation of Metastatic Eccrine Porocarcinoma: Case Study and Review of the Literature.. The American Journal of dermatopathology, 48(2), 125-131. https://doi.org/10.1097/DAD.0000000000003152
MLA Wang QX, et al.. "A Rare Clown Nose Manifestation of Metastatic Eccrine Porocarcinoma: Case Study and Review of the Literature.." The American Journal of dermatopathology, vol. 48, no. 2, 2026, pp. 125-131.
PMID 41592301

Abstract

The "clown nose" is a rare clinical presentation characterized by reddish-brown nodular lesions localized to the nasal tip. This distinctive sign has been associated with metastatic malignancies, genetic syndromes, and primary dermatologic conditions. We describe a rare case of metastatic eccrine porocarcinoma manifesting as a clown nose in a 54-year-old man with a history of metastatic lung squamous cell carcinoma. In addition, we performed a systematic literature review through PubMed to evaluate infiltration of the nose as a potential indicator of underlying tumor metastasis.

🏷️ 키워드 / MeSH