Invasive Lobular Carcinoma of the Male Breast With BRCA2 Mutation.
Male breast cancer (MBC) is a rare condition, accounting for < 1% of all breast cancer cases.
APA
Abe M, Saito F, et al. (2026). Invasive Lobular Carcinoma of the Male Breast With BRCA2 Mutation.. Case reports in pathology, 2026, 3580444. https://doi.org/10.1155/crip/3580444
MLA
Abe M, et al.. "Invasive Lobular Carcinoma of the Male Breast With BRCA2 Mutation.." Case reports in pathology, vol. 2026, 2026, pp. 3580444.
PMID
41769367
Abstract
Male breast cancer (MBC) is a rare condition, accounting for < 1% of all breast cancer cases. Reports of bilateral synchronous MBC are even more uncommon. Although lobular carcinoma is generally absent in the male mammary gland, a few cases of lobular carcinoma in MBC have been documented, comprising 1%-2% of all MBC cases. A man in his 80s presented to our hospital with a mass on his left nipple. After detailed examination, he was diagnosed with invasive ductal carcinoma of the left breast and invasive lobular carcinoma of the right breast. Because he had a family history of breast cancer, he underwent genetic testing and was found to have a gene mutation (c.331_347delinsC [p.Asn111Leufs∗5]). Simultaneous surgery was performed for bilateral breast cancer. Although drug therapy and radiation therapy were recommended after the operation, the patient was under observation due to his advanced age. A brief literature review is presented in this section.