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18FAl-NOTA-FAPI PET/CT Outperforms 18F-FDG PET/CT in Detecting Gastrointestinal Metastasis of Lobular Breast Carcinoma.

Clinical nuclear medicine 2026 Vol.51(3) p. e181-e182

Zhang A, Zu M, Ma Y, Ding S, Zhao M

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A 57-year-old woman with a history of right breast cancer surgery 22 years prior presented with CT findings of gastric and intestinal wall thickening, accompanied by mild-to-moderate FDG uptake on 18F

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APA Zhang A, Zu M, et al. (2026). 18FAl-NOTA-FAPI PET/CT Outperforms 18F-FDG PET/CT in Detecting Gastrointestinal Metastasis of Lobular Breast Carcinoma.. Clinical nuclear medicine, 51(3), e181-e182. https://doi.org/10.1097/RLU.0000000000006176
MLA Zhang A, et al.. "18FAl-NOTA-FAPI PET/CT Outperforms 18F-FDG PET/CT in Detecting Gastrointestinal Metastasis of Lobular Breast Carcinoma.." Clinical nuclear medicine, vol. 51, no. 3, 2026, pp. e181-e182.
PMID 41632581

Abstract

A 57-year-old woman with a history of right breast cancer surgery 22 years prior presented with CT findings of gastric and intestinal wall thickening, accompanied by mild-to-moderate FDG uptake on 18F-FDG PET/CT. Pathological results showed lobular breast cancer metastasis. The lesions showed significantly higher uptake on 18FAl-NOTA-FAPI PET/CT, and an additional sternal metastasis was identified.

MeSH Terms

Humans; Positron Emission Tomography Computed Tomography; Middle Aged; Fluorodeoxyglucose F18; Female; Breast Neoplasms; Carcinoma, Lobular; Gastrointestinal Neoplasms; Heterocyclic Compounds; Heterocyclic Compounds, 1-Ring

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