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Tucatinib-trastuzumab-capecitabine for treatment of leptomeningeal metastasis in women with HER2 breast cancer: TBCRC049 phase 2 study results.

1/5 보강
Nature cancer 📖 저널 OA 46.5% 2024: 1/1 OA 2025: 7/18 OA 2026: 12/24 OA 2024~2026 2026 Vol.7(3) p. 424-434
Retraction 확인
출처

PICO 자동 추출 (휴리스틱, conf 2/4)

유사 논문
P · Population 대상 환자/모집단
환자: newly diagnosed LM and human epidermal growth factor receptor 2-positive (HER2) breast cancer
I · Intervention 중재 / 시술
추출되지 않음
C · Comparison 대조 / 비교
추출되지 않음
O · Outcome 결과 / 결론
This prospective study suggests clinical benefit with a systemic regimen for HER2 LM including objective responses, improved symptoms and extended survival. These data support systemic therapy as an approach in HER2 breast cancer LM.

Murthy RK, O'Brien BJ, Berry DA, Singareeka-Raghavendra A, Monroe MG, Johnson J


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