Shadows and Light: The Evolution of Postmastectomy Radiation Therapy and Regional Nodal Irradiation in the Era of De-Escalation.
1/5 보강
PICO 자동 추출 (휴리스틱, conf 2/4)
유사 논문P · Population 대상 환자/모집단
환자: breast cancer
I · Intervention 중재 / 시술
추출되지 않음
C · Comparison 대조 / 비교
추출되지 않음
O · Outcome 결과 / 결론
Emphasis is placed on the evolution of patient selection, advances in fractionation, and the integration of new approaches. This is a story of progress, precision, and the pursuit of balance in the management of patients with breast cancer.
Radiation therapy represents a cornerstone in the management of breast cancer, from early-stage to advanced cancers.
APA
Shamsesfandabadi P, Rusia B, Shah C (2026). Shadows and Light: The Evolution of Postmastectomy Radiation Therapy and Regional Nodal Irradiation in the Era of De-Escalation.. JCO oncology practice, 22(3), 375-381. https://doi.org/10.1200/OP-25-00357
MLA
Shamsesfandabadi P, et al.. "Shadows and Light: The Evolution of Postmastectomy Radiation Therapy and Regional Nodal Irradiation in the Era of De-Escalation.." JCO oncology practice, vol. 22, no. 3, 2026, pp. 375-381.
PMID
40549989 ↗
Abstract 한글 요약
Radiation therapy represents a cornerstone in the management of breast cancer, from early-stage to advanced cancers. For appropriately selected patients, postmastectomy radiation therapy (PMRT) and regional nodal irradiation (RNI) have historically been shown to improve locoregional control and survival. However, PMRT is associated with an increased risk of cardiopulmonary toxicity, lymphedema, and reconstruction complications. This has led clinicians to re-evaluate a one-size-fits-all approach to PMRT and RNI, instead, looking for a more refined approach to maximizing the therapeutic ratio. This review explores the historical foundations, landmark trials, and paradigm-shifting updates that have transformed PMRT and RNI from broad, uniform strategies into nuanced, patient-specific therapies. Emphasis is placed on the evolution of patient selection, advances in fractionation, and the integration of new approaches. This is a story of progress, precision, and the pursuit of balance in the management of patients with breast cancer.
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🏷️ 같은 키워드 · 무료전문 — 이 논문 MeSH/keyword 기반
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