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Urachal cancer: a clinical, diagnostic, and therapeutic update.

Current opinion in urology 2026 Vol.36(2) p. 155-160

Reis H, Szarvas T, Paner GP

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[PURPOSE OF REVIEW] To give an overview of the advances in treatment, diagnosis, and epidemiological data of urachal tumors in 2024 and 2025.

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APA Reis H, Szarvas T, Paner GP (2026). Urachal cancer: a clinical, diagnostic, and therapeutic update.. Current opinion in urology, 36(2), 155-160. https://doi.org/10.1097/MOU.0000000000001360
MLA Reis H, et al.. "Urachal cancer: a clinical, diagnostic, and therapeutic update.." Current opinion in urology, vol. 36, no. 2, 2026, pp. 155-160.
PMID 41318990

Abstract

[PURPOSE OF REVIEW] To give an overview of the advances in treatment, diagnosis, and epidemiological data of urachal tumors in 2024 and 2025.

[RECENT FINDINGS] The update specifically refers to surgical approaches for localized cancers, drug therapy of advanced cancers, diagnostic criteria and consensus recommendations, diagnostic approaches, and epidemiological data.

[SUMMARY] Recommendations for partial cystectomy (if feasible) in localized urachal adenocarcinomas helps to standardize therapeutic approaches. In addition, current clinical trial results and running studies will help to personalize treatment decisions in advanced disease. The ISUP Dublin consensus recommendations will facilitate the diagnostic process and research, as will the summarized, unbiased epidemiological data.

MeSH Terms

Humans; Urinary Bladder Neoplasms; Cystectomy; Adenocarcinoma; Treatment Outcome; Practice Guidelines as Topic; Urachus; Neoplasm Staging