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OPTIMAL: A Multinational Phase III Study of Oral Paclitaxel (DHP107) versus Intravenous Weekly Paclitaxel in HER2-Negative Recurrent or Metastatic Breast Cancer.

1/5 보강
Annals of oncology : official journal of the European Society for Medical Oncology 📖 저널 OA 22.3% 2022: 1/2 OA 2023: 1/3 OA 2024: 0/5 OA 2025: 1/25 OA 2026: 20/75 OA 2022~2026 2026
Retraction 확인
출처
PubMed DOI

PICO 자동 추출 (휴리스틱, conf 3/4)

유사 논문
P · Population 대상 환자/모집단
549 patients were randomized to receive either DHP107 (n=277) or paclitaxel (n=272); 519 patients were included in the PPS.
I · Intervention 중재 / 시술
no prior chemotherapy in the metastatic setting
C · Comparison 대조 / 비교
추출되지 않음
O · Outcome 결과 / 결론
Quality of life was comparable between the two groups. [CONCLUSIONS] DHP107 demonstrated non-inferior efficacy compared to IV paclitaxel, with a manageable safety profile, supporting its use as an effective and convenient alternative in HER2-negative breast cancer.

Xu B, Jeong H, Sun T, Sohn J, Zhang Q, Kostic S

PubMed ↗ DOI ↗ BibTeX ↓ RIS ↓

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