Intradural spinal bizarre parosteal osteochondromatous proliferation (BPOP): case report and review of the literature.
증례보고
1/5 보강
Bizarre parosteal osteochondromatous proliferation (BPOP), or Nora's lesion, is a benign but locally aggressive osteochondroid proliferation that almost exclusively involves the small bones of the han
APA
Nahal A, Elgamal EA, et al. (2026). Intradural spinal bizarre parosteal osteochondromatous proliferation (BPOP): case report and review of the literature.. Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 42(1). https://doi.org/10.1007/s00381-026-07186-z
MLA
Nahal A, et al.. "Intradural spinal bizarre parosteal osteochondromatous proliferation (BPOP): case report and review of the literature.." Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, vol. 42, no. 1, 2026.
PMID
41779169 ↗
Abstract 한글 요약
Bizarre parosteal osteochondromatous proliferation (BPOP), or Nora's lesion, is a benign but locally aggressive osteochondroid proliferation that almost exclusively involves the small bones of the hands and feet. Spinal involvement is exceptionally rare, with only two cases previously reported. We describe a 13-year-old boy who presented with progressive lower-limb weakness, gait instability, urinary urgency, and significant weight loss. MRI demonstrated a well-circumscribed intradural extramedullary mass at L1 with mixed signal characteristics and peripheral enhancement, initially raising concern for neoplastic or vascular pathology. Surgical resection via L1 laminotomy revealed a firm, partially mineralized lesion densely adherent to several nerve roots. Histopathologic examination showed hypercellular cartilage, immature "blue bone," and reactive osteoblastic rimming, establishing the diagnosis of BPOP. Postoperative recovery demonstrated partial neurological improvement. This case represents the third reported spinal BPOP and the first pediatric case. Its highly unusual intradural location and deceptive imaging appearance highlight the importance of considering BPOP in the differential diagnosis of mineralized intradural masses. Early recognition is critical to avoid overtreatment and to guide long-term surveillance given the lesion's propensity for recurrence.
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