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Engineered outer membrane vesicles enhance solid tumour CAR-T cell therapy.

3/5 보강
Nature biomedical engineering 📖 저널 OA 36% 2023: 0/1 OA 2025: 1/4 OA 2026: 8/20 OA 2023~2026 2026 Vol.10(4) p. 660-675 cited 10 OA CAR-T cell therapy research
TL;DR A bacterial OMV-based immunosuppression reversal and optimized antigen decoration platform for CAR-T therapy (BROAD-CAR), in which OMVs are modified to express a high-affinity anti-PD-L1 antibody and load plasmids encoding the target antigen for CARs, highlights a safe and efficient approach to enhance the efficacy and applicability of CAR-T therapy in solid tumours.
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PubMed DOI PMC OpenAlex Semantic 마지막 보강 2026-05-01
OpenAlex 토픽 · CAR-T cell therapy research Cancer Research and Treatments Monoclonal and Polyclonal Antibodies Research

Li X, Li X, Shi J, Li Y, Zhang H, Chen T

📖 무료 전문 🟢 PMC 전문 PMC13099647 🔓 OA PDF oa
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