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Hyalinizing Clear Cell Carcinoma of the Thymus Predominantly Composed of Eosinophilic Cells: A Case Report and Literature Review.

International journal of surgical pathology 2026 Vol.34(2) p. 536-541

Zeng Y, Lv L, Fu P, Luo L

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Clear cell carcinoma of the thymus is a rare malignant neoplasm originating from the thymus.

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APA Zeng Y, Lv L, et al. (2026). Hyalinizing Clear Cell Carcinoma of the Thymus Predominantly Composed of Eosinophilic Cells: A Case Report and Literature Review.. International journal of surgical pathology, 34(2), 536-541. https://doi.org/10.1177/10668969251382663
MLA Zeng Y, et al.. "Hyalinizing Clear Cell Carcinoma of the Thymus Predominantly Composed of Eosinophilic Cells: A Case Report and Literature Review.." International journal of surgical pathology, vol. 34, no. 2, 2026, pp. 536-541.
PMID 41066478

Abstract

Clear cell carcinoma of the thymus is a rare malignant neoplasm originating from the thymus. Hyalinizing clear cell carcinoma of the thymus is an exceptionally rare subtype and poses significant diagnostic challenges when predominantly composed of eosinophilic cells. Here, we present a case report of thymic hyalinizing clear cell carcinoma predominantly composed of eosinophilic cells, along with a comprehensive literature review analyzing its clinical, histopathological, immunohistochemical, and molecular characteristics.

MeSH Terms

Humans; Thymus Neoplasms; Adenocarcinoma, Clear Cell; Thymus Gland; Male; Eosinophils; Biomarkers, Tumor; Hyalin; Middle Aged; Female

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