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Optimizing Options for Future Third-Party Reproduction Among Youth Newly Diagnosed With Cancer: Considerations for Pediatric Fertility Preservation Counseling.

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Pediatric blood & cancer 📖 저널 OA 42.3% 2022: 0/2 OA 2023: 2/3 OA 2025: 2/16 OA 2026: 48/101 OA 2022~2026 2026 Vol.73(4) p. e70119 OA Reproductive Biology and Fertility
TL;DR Challenges, opportunities, and clinical decision trees for discussing TPR during pediatric fertility consultations are presented, emphasizing collaboration with adult reproductive clinics to support survivors’ long‐term reproductive goals.
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PubMed DOI OpenAlex Semantic 마지막 보강 2026-05-01
OpenAlex 토픽 · Reproductive Biology and Fertility Reproductive Health and Technologies Assisted Reproductive Technology and Twin Pregnancy

Klosky JL, Cherven B, Lehmann V, Chan SH, Rios JM, Su HI

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Challenges, opportunities, and clinical decision trees for discussing TPR during pediatric fertility consultations are presented, emphasizing collaboration with adult reproductive clinics to support s

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APA James L. Klosky, Brooke Cherven, et al. (2026). Optimizing Options for Future Third-Party Reproduction Among Youth Newly Diagnosed With Cancer: Considerations for Pediatric Fertility Preservation Counseling.. Pediatric blood & cancer, 73(4), e70119. https://doi.org/10.1002/1545-5017.70119
MLA James L. Klosky, et al.. "Optimizing Options for Future Third-Party Reproduction Among Youth Newly Diagnosed With Cancer: Considerations for Pediatric Fertility Preservation Counseling.." Pediatric blood & cancer, vol. 73, no. 4, 2026, pp. e70119.
PMID 41579040 ↗

Abstract

Children with cancer are at-risk for infertility, yet most desire biological parenthood. Fertility preservation is available for pre- and postpubertal patients, with tissues typically banked for autologous use. Some survivors require third-party reproduction (TPR) but do not complete the Food and Drug Administration (FDA)-required donor eligibility steps when banking their reproductive materials. This article reviews medical and nonmedical factors associated with TPR, FDA regulatory requirements, risks of non-compliance, and recommendations for facilitation in the pediatric oncology setting. Challenges, opportunities, and clinical decision trees for discussing TPR during pediatric fertility consultations are presented, emphasizing collaboration with adult reproductive clinics to support survivors' long-term reproductive goals.

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