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DNA methylation as a predictor of pituitary neuroendocrine tumour behaviour: A systematic review.

메타분석 1/5 보강
Journal of neuroendocrinology 2026 Vol.38(4) p. e70167
Retraction 확인
출처
PubMed DOI PMC

PICO 자동 추출 (휴리스틱, conf 2/4)

유사 논문
P · Population 대상 환자/모집단
These analyses identified several differentially methylated genes linked to invasiveness (e.g., PHYHD1, WNT4, STAT6, CDH1, CDH13), aggressive behaviour (e.g., AIP, PDCD1, LINE-1), and tumour regrowth (e.g., TERT, FAM90A1, ING2).
I · Intervention 중재 / 시술
추출되지 않음
C · Comparison 대조 / 비교
추출되지 않음
O · Outcome 결과 / 결론
DNA methylation profiling shows potential for predicting PitNET behaviour, but methodological inconsistencies limit its clinical application. Standardized methods and prospective validation are needed for clinical integration.

van der Groef R, Mulugeta E, Neggers S, Refardt J

📖 무료 전문 🟢 PMC 전문 PMC13006151
PubMed ↗ DOI ↗ BibTeX ↓ RIS ↓

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