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PPhMe-Promoted [4 + 3] Annulation for Synthesis of Quinazoline-Fused Benzothiadiazepines as Anti-Breast Cancer Agents.

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Chemistry (Weinheim an der Bergstrasse, Germany) 2026 Vol.32(14) p. e03547 Quinazolinone synthesis and applicat
TL;DR Preliminary mechanistic insights from molecular docking studies indicated binding affinity to the EGFR kinase active site, which provides a testable hypothesis for the mechanism of action and established the scaffold's promising preliminary anti-TNBC profile.
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PubMed DOI OpenAlex Semantic 마지막 보강 2026-04-30
OpenAlex 토픽 · Quinazolinone synthesis and applications Synthesis and pharmacology of benzodiazepine derivatives Synthesis and bioactivity of alkaloids

Sun PF, Wang YJ, Liao YH, Jing WS, Zhao LM

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