Improving immunotherapy in solid tumors using FMT.
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OpenAlex 토픽 ·
Immunotherapy and Immune Responses
Cancer Research and Treatments
Monoclonal and Polyclonal Antibodies Research
Recent clinical trials demonstrate that fecal microbiota transplantation (FMT) enhances first-line immune checkpoint inhibitor efficacy in renal cell carcinoma, cutaneous melanoma, and non-small cell
APA
Diwakar Davar, Hassane M. Zarour, Georgio Trinchieri (2026). Improving immunotherapy in solid tumors using FMT.. Cell, 189(8), 2214-2217. https://doi.org/10.1016/j.cell.2026.03.021
MLA
Diwakar Davar, et al.. "Improving immunotherapy in solid tumors using FMT.." Cell, vol. 189, no. 8, 2026, pp. 2214-2217.
PMID
41997122 ↗
Abstract 한글 요약
Recent clinical trials demonstrate that fecal microbiota transplantation (FMT) enhances first-line immune checkpoint inhibitor efficacy in renal cell carcinoma, cutaneous melanoma, and non-small cell lung cancer with acceptable safety. Benefit appears mediated by functional microbiome remodeling, depletion of deleterious taxa, and systemic immunometabolic modulation, supporting microbiome-directed therapeutic strategies for cancer immunotherapy.
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