[Establishment of rabbit orbital hypertelorism model and evaluation of effects of surgical correction].

Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2006 Vol.26(10) p. 1476-7, 1480

Yuan Q, Liu DL, Yuan JL, Shan L

Abstract

[OBJECTIVE] To establish a rabbit model of orbital hypertelorism for plastic and reconstructive surgery and evaluate the surgical effects.

[METHODS] Orbital osteotomies and medial translocation was performed in 16 New Zealand rabbits (4 to 6 months old) by combined intracranial-extracranial approach. The interorbital distance (IOD) and bone healing between the orbits were evaluated with gross measurement. X-ray and histological examinations were performed immediately and 12 weeks after the operation.

[RESULTS] The average IOD of the rabbits was 0.74 cm after completion of the operation, but increased to 0.96 cm 12 weeks after the operation, showing significant relapse of orbital hypertelorism (P<0.01).

[CONCLUSION] The IOD can be decreased successfully in this rabbit model.

추출된 의학 개체 (NER)

유형영어 표현한국어 / 풀이UMLS CUI출처등장
해부 medial scispacy 1
해부 bone scispacy 1
약물 [OBJECTIVE] scispacy 1
질환 rabbit orbital hypertelorism C0020534
Orbital separation excessive
scispacy 1
질환 orbital hypertelorism C0020534
Orbital separation excessive
scispacy 1
기타 rabbit orbital scispacy 1
기타 rabbit scispacy 1
기타 rabbits scispacy 1

MeSH Terms

Animals; Disease Models, Animal; Female; Hypertelorism; Male; Rabbits; Plastic Surgery Procedures; Surgery, Plastic