Management of non-detection of the sentinel node in breast cancer: A scoping review.
리뷰
2/5 보강
OpenAlex 토픽 ·
Breast Cancer Treatment Studies
Breast Lesions and Carcinomas
Estrogen and related hormone effects
Axillary nodal status is a key prognostic factor in women with breast cancer and is most commonly assessed by sentinel lymph node biopsy (SLNB).
APA
Lærke Smedegaard Andersen, Katrine Jensen, Tove Holst Filtenborg Tvedskov (2026). Management of non-detection of the sentinel node in breast cancer: A scoping review.. European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 52(5), 111790. https://doi.org/10.1016/j.ejso.2026.111790
MLA
Lærke Smedegaard Andersen, et al.. "Management of non-detection of the sentinel node in breast cancer: A scoping review.." European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, vol. 52, no. 5, 2026, pp. 111790.
PMID
41966790 ↗
Abstract 한글 요약
Axillary nodal status is a key prognostic factor in women with breast cancer and is most commonly assessed by sentinel lymph node biopsy (SLNB). However, non-detection of the sentinel node occurs in 1-13% of cases and remains insufficiently addressed in international clinical guidelines. This scoping review maps the existing evidence on axillary sampling (AS) as an alternative axillary staging strategy when the sentinel node cannot be identified. A structured literature search was conducted in PubMed to identify studies evaluating the diagnostic accuracy of AS in comparison with SLNB and axillary lymph node dissection (ALND) in clinically node-negative breast cancer. Nine studies, reported in ten publications, met the eligibility criteria. Across the included literature, AS demonstrated high sensitivity and low false-negative rates, particularly when four or more lymph nodes were removed. The diagnostic performance of AS was comparable to ALND and slightly inferior to SLNB. Overall, the available evidence suggests that AS may represent a feasible alternative for axillary staging in cases of sentinel node non-detection. However, the evidence base is limited and largely derived from older studies, highlighting the need for contemporary research to inform clinical practice and guideline development.
🏷️ 키워드 / MeSH 📖 같은 키워드 OA만
🏷️ 같은 키워드 · 무료전문 — 이 논문 MeSH/keyword 기반
- A Phase I Study of Hydroxychloroquine and Suba-Itraconazole in Men with Biochemical Relapse of Prostate Cancer (HITMAN-PC): Dose Escalation Results.
- Self-management of male urinary symptoms: qualitative findings from a primary care trial.
- Clinical and Liquid Biomarkers of 20-Year Prostate Cancer Risk in Men Aged 45 to 70 Years.
- Diagnostic accuracy of Ga-PSMA PET/CT versus multiparametric MRI for preoperative pelvic invasion in the patients with prostate cancer.
- Association of patient health education with the postoperative health related quality of life in low- intermediate recurrence risk differentiated thyroid cancer patients.
- Early local immune activation following intra-operative radiotherapy in human breast tissue.