A novel triphenylamine-based aggregation-induced emission (AIE) probe for breast cancer imaging in vitro and in vivo.
2/5 보강
OpenAlex 토픽 ·
Luminescence and Fluorescent Materials
Nanoplatforms for cancer theranostics
Molecular Sensors and Ion Detection
Aggregation-induced emission (AIE) probes have attracted considerable interest in bioanalysis because of their good photostability, high imaging contrast, and longtime tracing capability.
APA
Xiaohui Teng, Mengjiao Wang, et al. (2026). A novel triphenylamine-based aggregation-induced emission (AIE) probe for breast cancer imaging in vitro and in vivo.. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 354, 127638. https://doi.org/10.1016/j.saa.2026.127638
MLA
Xiaohui Teng, et al.. "A novel triphenylamine-based aggregation-induced emission (AIE) probe for breast cancer imaging in vitro and in vivo.." Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, vol. 354, 2026, pp. 127638.
PMID
41762799 ↗
Abstract 한글 요약
Aggregation-induced emission (AIE) probes have attracted considerable interest in bioanalysis because of their good photostability, high imaging contrast, and longtime tracing capability. Herein, we developed a new AIE-active probe, AIE-BC, by conjugating triphenylamine (TPA) to bithiophene via Suzuki coupling reaction. AIE-BC exhibited AIE character, excellent photostability, and superior biocompatibility. Flow cytometry analyzes revealed that AIE-BC was selectively taken up by MCF-7 cells, a result complemented by clear in vitro cellular images obtained from confocal microscopy. Further in vivo and ex vivo imaging studies demonstrated that AIE-BC could effectively accumulate in the tumor region. In conclusion, this research presents a promising AIE probe for the real-time detection of breast cancer.
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