IgD Multiple Myeloma: a Rare and Aggressive Entity: Report of Three Clinical Cases and Review of the Literature.
2/5 보강
PICO 자동 추출 (휴리스틱, conf 2/4)
유사 논문P · Population 대상 환자/모집단
환자: a mean age of 38 years
I · Intervention 중재 / 시술
추출되지 않음
C · Comparison 대조 / 비교
추출되지 않음
O · Outcome 결과 / 결론
[CONCLUSIONS] Compared to existing literature, our series aligns with the known features of IgD myeloma, including male predominance, lambda light chain involvement, anemia, renal dysfunction, and lytic bone lesions. However, it is distinguished by the unusually young age of the patients, highlighting the need for heightened clinical suspicion in younger individuals presenting with such symptoms.
OpenAlex 토픽 ·
Multiple Myeloma Research and Treatments
Viral-associated cancers and disorders
Chronic Myeloid Leukemia Treatments
[BACKGROUND] IgD multiple myeloma is an exceptionally rare subtype, accounting for less than 2% of all multiple myeloma cases.
APA
El Mostafa Chachi, Mounya Bouabdellah, et al. (2026). IgD Multiple Myeloma: a Rare and Aggressive Entity: Report of Three Clinical Cases and Review of the Literature.. Clinical laboratory, 72(3). https://doi.org/10.7754/Clin.Lab.2025.250567
MLA
El Mostafa Chachi, et al.. "IgD Multiple Myeloma: a Rare and Aggressive Entity: Report of Three Clinical Cases and Review of the Literature.." Clinical laboratory, vol. 72, no. 3, 2026.
PMID
41945733 ↗
Abstract 한글 요약
[BACKGROUND] IgD multiple myeloma is an exceptionally rare subtype, accounting for less than 2% of all multiple myeloma cases.
[METHODS] We report three cases diagnosed at the central biochemistry laboratory of the Ibn Sina University Hospital in Rabat, Morocco, involving young patients with a mean age of 38 years.
[RESULTS] All cases showed a marked male predominance. Clinically, patients presented with frequent bone involvement and renal impairment. Laboratory findings consistently revealed anemia, Bence-Jones proteinuria with a predominance of lambda light chains, hypercalcemia, and variable bone marrow infiltration by plasma cells, reaching up to 88%. The diagnosis is often challenging due to the subtle or absent monoclonal bands on serum protein electrophoresis.
[CONCLUSIONS] Compared to existing literature, our series aligns with the known features of IgD myeloma, including male predominance, lambda light chain involvement, anemia, renal dysfunction, and lytic bone lesions. However, it is distinguished by the unusually young age of the patients, highlighting the need for heightened clinical suspicion in younger individuals presenting with such symptoms.
[METHODS] We report three cases diagnosed at the central biochemistry laboratory of the Ibn Sina University Hospital in Rabat, Morocco, involving young patients with a mean age of 38 years.
[RESULTS] All cases showed a marked male predominance. Clinically, patients presented with frequent bone involvement and renal impairment. Laboratory findings consistently revealed anemia, Bence-Jones proteinuria with a predominance of lambda light chains, hypercalcemia, and variable bone marrow infiltration by plasma cells, reaching up to 88%. The diagnosis is often challenging due to the subtle or absent monoclonal bands on serum protein electrophoresis.
[CONCLUSIONS] Compared to existing literature, our series aligns with the known features of IgD myeloma, including male predominance, lambda light chain involvement, anemia, renal dysfunction, and lytic bone lesions. However, it is distinguished by the unusually young age of the patients, highlighting the need for heightened clinical suspicion in younger individuals presenting with such symptoms.
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