Management of Anaplastic Large Cell Lymphoma.
Abstract
Anaplastic large cell lymphoma (ALCL) is one of the most common peripheral T-cell lymphomas, and the incidence is higher in blacks than non-Hispanic whites. ALK-positive and ALK-negative ALCL are distinct subtypes that have different characteristics and clinical outcomes. Breast implant-associated ALCL is a rare lymphoma that has a good survival outcome, and a recent study showed that total capsulectomy is essential for treatment. Brentuximab vedotin (BV) is a standard treatment for relapsed/refractory ALCL. The response rate is high at 80-90%; however, once the disease progresses in patients on BV, survival outcome is very poor, with a median overall survival of less than two months.
추출된 의학 개체 (NER)
| 유형 | 영어 표현 | 한국어 / 풀이 | UMLS CUI | 출처 | 등장 |
|---|---|---|---|---|---|
| 합병증 | anaplastic large cell lymphoma
|
보형물연관 역형성대세포림프종 | dict | 2 | |
| 해부 | breast
|
유방 | dict | 1 | |
| 약물 | Brentuximab vedotin
|
C2973446
brentuximab vedotin
|
scispacy | 1 | |
| 질환 | Anaplastic
|
C0205618
Undifferentiated
|
scispacy | 1 | |
| 질환 | large cell lymphoma
|
C0024302
Reticulosarcoma
|
scispacy | 1 | |
| 질환 | ALCL
→ Anaplastic large cell lymphoma
|
C0206180
Ki-1+ Anaplastic Large Cell Lymphoma
|
scispacy | 1 | |
| 질환 | peripheral T-cell lymphomas
|
C0079774
Peripheral T-Cell Lymphoma
|
scispacy | 1 | |
| 질환 | ALK-positive
|
C4290023
ALK Positive
|
scispacy | 1 | |
| 질환 | ALK-negative ALCL
|
scispacy | 1 | ||
| 질환 | Breast implant-associated ALCL
|
scispacy | 1 | ||
| 질환 | lymphoma
|
scispacy | 1 | ||
| 기타 | patients
|
scispacy | 1 |
MeSH Terms
Breast Implants; Brentuximab Vedotin; Disease-Free Survival; Female; Humans; Immunoconjugates; Lymphoma, Large-Cell, Anaplastic; Male; Survival Rate
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