"Surgical technique: A novel pedicled periosteal scapular flap to facilitate bone growth in an Ovine model".
Abstract
[BACKGROUND] Vascularised periosteum can used for reconstructing bony defects due to its intrinsic osteogenic properties. This osteogenic potential can be harnessed as a vascularised flap to induce bone growth of complex constructs in-vivo. The authors aimed to use a novel pedicled periosteal flap from the scapula to induce bone growth in a critical sized construct.
[METHODS] Eight sheep were used as live animal models. A novel periosteal flap was raised from the infraspinous fossa of each animal and wrapped around non-vascularised autologous bone graft. The constructs were allowed to incubate between 1 and 84 days before harvest. Analysis of the flap was done via histopathology using haematoxylin and eosin staining.
[RESULTS] All flaps were viable at the conclusion of surgery. Seven flaps showed variable thickening with matrix deposition. One flap was devitalised at time of harvest.
[CONCLUSION] The novel periosteal scapular flap described is a promising technique to induce bone growth in complex constructs.
[METHODS] Eight sheep were used as live animal models. A novel periosteal flap was raised from the infraspinous fossa of each animal and wrapped around non-vascularised autologous bone graft. The constructs were allowed to incubate between 1 and 84 days before harvest. Analysis of the flap was done via histopathology using haematoxylin and eosin staining.
[RESULTS] All flaps were viable at the conclusion of surgery. Seven flaps showed variable thickening with matrix deposition. One flap was devitalised at time of harvest.
[CONCLUSION] The novel periosteal scapular flap described is a promising technique to induce bone growth in complex constructs.
추출된 의학 개체 (NER)
| 유형 | 영어 표현 | 한국어 / 풀이 | UMLS CUI | 출처 | 등장 |
|---|---|---|---|---|---|
| 시술 | flap
|
피판재건술 | dict | 7 | |
| 해부 | bone
|
scispacy | 1 | ||
| 해부 | bone graft
|
scispacy | 1 | ||
| 해부 | matrix
|
scispacy | 1 | ||
| 합병증 | periosteal flap
|
scispacy | 1 | ||
| 합병증 | scapula
|
scispacy | 1 | ||
| 합병증 | infraspinous fossa
|
scispacy | 1 | ||
| 약물 | [BACKGROUND] Vascularised periosteum can
|
scispacy | 1 | ||
| 기타 | pedicled periosteal scapular
|
scispacy | 1 | ||
| 기타 | Ovine
|
scispacy | 1 | ||
| 기타 | sheep
|
scispacy | 1 | ||
| 기타 | devitalised
|
scispacy | 1 | ||
| 기타 | periosteal scapular flap
|
scispacy | 1 |
MeSH Terms
Animals; Bone Transplantation; Humans; Osteogenesis; Periosteum; Scapula; Sheep; Surgical Flaps
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