"Surgical technique: A novel pedicled periosteal scapular flap to facilitate bone growth in an Ovine model".

Journal of plastic, reconstructive & aesthetic surgery : JPRAS 2022 Vol.75(4) p. 1497-1520

Ghosh YA, Gupta R, Al Maruf DA, Cheng K, Mukherjee P, Clark JR

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Abstract

[BACKGROUND] Vascularised periosteum can used for reconstructing bony defects due to its intrinsic osteogenic properties. This osteogenic potential can be harnessed as a vascularised flap to induce bone growth of complex constructs in-vivo. The authors aimed to use a novel pedicled periosteal flap from the scapula to induce bone growth in a critical sized construct.

[METHODS] Eight sheep were used as live animal models. A novel periosteal flap was raised from the infraspinous fossa of each animal and wrapped around non-vascularised autologous bone graft. The constructs were allowed to incubate between 1 and 84 days before harvest. Analysis of the flap was done via histopathology using haematoxylin and eosin staining.

[RESULTS] All flaps were viable at the conclusion of surgery. Seven flaps showed variable thickening with matrix deposition. One flap was devitalised at time of harvest.

[CONCLUSION] The novel periosteal scapular flap described is a promising technique to induce bone growth in complex constructs.

추출된 의학 개체 (NER)

유형영어 표현한국어 / 풀이UMLS CUI출처등장
시술 flap 피판재건술 dict 7
해부 bone scispacy 1
해부 bone graft scispacy 1
해부 matrix scispacy 1
합병증 periosteal flap scispacy 1
합병증 scapula scispacy 1
합병증 infraspinous fossa scispacy 1
약물 [BACKGROUND] Vascularised periosteum can scispacy 1
기타 pedicled periosteal scapular scispacy 1
기타 Ovine scispacy 1
기타 sheep scispacy 1
기타 devitalised scispacy 1
기타 periosteal scapular flap scispacy 1

MeSH Terms

Animals; Bone Transplantation; Humans; Osteogenesis; Periosteum; Scapula; Sheep; Surgical Flaps

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